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Epigenetic mechanisms, such as acetylation, methylation, and succinylation, play pivotal
roles in the regulation of multiple normal biological processes, including neuron regulation …

Histone deacetylase 11 (HDAC11) is the only member of the class IV HDAC, and the latest
member identified. It is highly expressed in brain, heart, kidney and some other organs, and …

Simple Summary Pancreatic neuroendocrine tumors (pNETs) are rare, indolent cancers
whose causation is only partly understood. An increasing number of studies have uncovered …

Both somatostatin (SST) and somatostatin receptors (SSTRs) are proteins with important
functions in both physiological tissue and in tumors, particularly in neuroendocrine tumors …

Abstract Histone deacetylase 11 (HDAC11) is a unique member of the histone deacetylase
family that plays an important role in the regulation of gene expression and protein function …

Among the epigenetic changes, histone acetylation has been recognized as a fundamental
process that strongly affects gene expression regulation. Disrupt of this phenomenon has …

The histone deacetylases (HDACs) family of enzymes possess deacylase activity for histone
and nonhistone proteins; HDAC11 is the latest discovered HDAC and the only member of …

Introduction: Recent advances in diagnostic modalities and therapeutic agents have raised
the importance of prognostic factors in predicting overall survival, as well as predictive …

Small cell lung cancer (SCLC) is a particular subtype of lung cancer with high mortality.
Recent advances in understanding SCLC genomics and breakthroughs of immunotherapy …