Nanocarrier mediated drug delivery as an impeccable therapeutic approach against Alzheimer's disease
For the past several years, dementia, is one of the predominantly observed groups of
symptoms in a geriatric population. Alzheimer's disease (AD) is a progressive memory …
symptoms in a geriatric population. Alzheimer's disease (AD) is a progressive memory …
DoE-enhanced development and validation of eco-friendly RP-HPLC method for analysis of safinamide and its precursor impurity: QbD approach
HM El-Sayed, HE Abdellatef, HAM Hendawy… - Microchemical …, 2023 - Elsevier
Abstract Design of Experiment (DoE) is an effective methodology for studying the
relationship between variables and their dependent responses. In this study, DoE was …
relationship between variables and their dependent responses. In this study, DoE was …
Analytical 'Quality-by-Design'paradigm in development of a RP-HPLC method for the estimation of cilnidipine in nanoformulations: Forced degradation studies and …
SM Marques, RK Shirodkar, L Kumar - Microchemical Journal, 2023 - Elsevier
The present study focuses on optimizing, developing, and validating a sensitive and specific
reversed-phase high-performance liquid chromatography (RP-HPLC) method for the …
reversed-phase high-performance liquid chromatography (RP-HPLC) method for the …
Development and characterization of hyaluronic acid surface scaffolds Encorafenib loaded polymeric nanoparticles for colorectal cancer targeting
For treatment of colorectal cancer and to improve intravascular bioavailability, Encorafenib
(ECF) encapsulated Hyaluronic Acid (HA) decorated polycaprolactone (PCL), and …
(ECF) encapsulated Hyaluronic Acid (HA) decorated polycaprolactone (PCL), and …
Analytical quality by design approach to develop an eco-friendly RP-HPLC method for estimation of irbesartan in chitosan polymeric nanoparticles: forced degradation …
SB Gopalaiah, K Jayaseelan - RSC advances, 2024 - pubs.rsc.org
Irbesartan is an angiotensin converting enzyme blocker, primarily utilized for the
management of hypertension and the mitigation of diabetic nephropathy progression. The …
management of hypertension and the mitigation of diabetic nephropathy progression. The …
Nanoparticle delivery for central nervous system diseases and its clinical application
L Tang, R Zhang, Y Wang, M Liu, D Hu, Y Wang… - Nano Research, 2024 - Springer
In the treatment of central nervous system (CNS) diseases such as glioma, Alzheimer's
disease (AD) and Parkinson's disease (PD), drugs are expected to reach specific areas of …
disease (AD) and Parkinson's disease (PD), drugs are expected to reach specific areas of …
PEGylated Polymer–Lipid Hybrid Nanoparticles to Enhance In Vivo Exposure and Uptake of Repaglinide in Brain Cells to Treat Diabetes-Linked Neurodegenerative …
Repaglinide (REP), an antidiabetic drug, is recently explored in ameliorating
neurodegenerative disorders (Huntington's and Alzheimer's disease) by targeting neuronal …
neurodegenerative disorders (Huntington's and Alzheimer's disease) by targeting neuronal …
QbD and Six Sigma quality approach for chromatographic estimation of repurposed simvastatin from nanostructured lipid carriers
The present research aimed to develop a simple, rapid, and sensitive RP-HPLC method for
the estimation of repurposed simvastatin (SMV) from nanostructured lipid carriers (NLCs) …
the estimation of repurposed simvastatin (SMV) from nanostructured lipid carriers (NLCs) …
QbD-driven RP-HPLC method for novel chemo-herbal combination, in-silico, force degradation studies, and characterization of dual drug-loaded polymeric and lipidic …
Background In cancer therapies, chemo-herbal combinations are receiving increased
attention. A multiple tyrosine kinase inhibitor, lenvatinib (LTB) is beneficial in treating thyroid …
attention. A multiple tyrosine kinase inhibitor, lenvatinib (LTB) is beneficial in treating thyroid …
A Quality by Design (QbD) driven gradient high performance liquid chromatography method development for the simultaneous estimation of dasatinib and nilotinib in …
S Sen, OP Ranjan - Journal of Chromatography B, 2024 - Elsevier
Tyrosine kinase inhibitors (TKIs) are effective as a targeted treatment for chronic myeloid
leukemia (CML), which can selectively suppress BCR-ABL1 kinase activity. CML therapy …
leukemia (CML), which can selectively suppress BCR-ABL1 kinase activity. CML therapy …