Pigs have substantial potential as biomedical models for studying human developmental
processes, congenital diseases, and pathogen response mechanisms in addition to utility as …

Animal models of human diseases play a critical role in medical research. Pigs are
anatomically and physiologically more like humans than are small rodents such as mice …

The testis must create and maintain an immune privileged environment to protect maturing
germ cells from autoimmune destruction. The establishment of this protective environment is …

Understanding biological mechanisms is fundamental for improving animal production and
health to meet the growing demand for high-quality protein. As an emerging biotechnology …

The large animal model has gradually become an essential part of preclinical research
studies, relating to exploring the disease pathological mechanism, genic function, pharmacy …

Sertoli cells (SCs) are immune privileged cells found in the testis that function to
immunologically protect maturing germ cells from immune destruction. This immune …

Abstract On 19-21 November 2020, the meeting of the 30 years of the Padova Muscle Days
was virtually held while the SARS-CoV-2 epidemic was hitting the world after a seemingly …

The Sertoli cells (SeCs) of the seminiferous tubules secrete a multitude of immunoregulatory
and trophic factors to provide immune protection and assist in the orderly development of …

Duchenne muscular dystrophy (DMD) is an X-linked disease caused by mutations in DMD
gene translating in lack of functional dystrophin and resulting in susceptibility of myofibers to …

Cell therapy could form part of the future treatment of degenerative disorders of genetic
origin that affect skeletal muscles, such as muscular dystrophies. This strategy could …