Systemic impacts of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) on heart, muscle …

R Sandireddy, S Sakthivel, P Gupta, J Behari… - Frontiers in cell and …, 2024 - frontiersin.org
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-
alcoholic fatty liver disease (NAFLD), is the most common liver disorder worldwide, with an …

Role of steatotic liver disease in prediction and prevention of cardiometabolic diseases

N Stefan, A Lonardo, G Targher - Nature Reviews Gastroenterology & …, 2024 - nature.com
Role of steatotic liver disease in prediction and prevention of cardiometabolic diseases |
Nature Reviews Gastroenterology & Hepatology Skip to main content Thank you for visiting …

Dissecting causal relationships between nonalcoholic fatty liver disease proxied by chronically elevated alanine transaminase levels and 34 extrahepatic diseases

Z Liu, C Suo, H Fan, T Zhang, L Jin, X Chen - Metabolism, 2022 - Elsevier
Background Nonalcoholic fatty liver disease (NAFLD) is prevalent worldwide and is
associated with the risk of many extrahepatic diseases. However, whether NAFLD is a risk …

Role of insulin resistance in the development of nonalcoholic fatty liver disease in people with type 2 diabetes: from bench to patient care

JP Nogueira, K Cusi - Diabetes Spectrum, 2024 - Am Diabetes Assoc
Insulin resistance is implicated in both the pathogenesis of nonalcoholic fatty liver disease
(NAFLD) and its progression from steatosis to steatohepatitis, cirrhosis, and even …

Assessing the causal relationships between human blood metabolites and the risk of NAFLD: A comprehensive mendelian randomization study

Z Guo, T Zhang, Z Yun, Q Jin, X Cao, D Kong… - Frontiers in …, 2023 - frontiersin.org
Background: Non-alcoholic fatty liver disease (NAFLD) is a liver disease associated with
obesity, insulin resistance, type 2 diabetes mellitus (T2DM), and metabolic syndrome. The …

NAFLD in cardiovascular diseases: A contributor or comorbidity?

B Chen, WHW Tang, M Rodriguez… - Seminars in liver …, 2022 - thieme-connect.com
Nonalcoholic fatty liver disease (NAFLD) and cardiovascular diseases are both highly
prevalent conditions around the world, and emerging data have shown an association …

[HTML][HTML] Differing genetic variants associated with liver fat and their contrasting relationships with cardiovascular diseases and cancer

A Ahmed, M Cule, JD Bell, N Sattar, H Yaghootkar - Journal of Hepatology, 2024 - Elsevier
Background & Aims The mechanisms underlying the association of steatotic liver disease
with cardiovascular and cancer outcomes are poorly understood. We aimed to use MRI …

Non‐alcoholic fatty liver disease and complications in type 1 and type 2 diabetes: a Mendelian randomization study

N Liu, G Wang, C Liu, J Liu, S Huang… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim To investigate the potential causal relationship between non‐alcoholic fatty liver
disease (NAFLD) and complications in type 1 diabetes (T1D) and type 2 diabetes (T2D) …

Genetic risk of fatty liver disease and mortality in the general population: A Mendelian randomization study

H Gellert‐Kristensen, A Tybjærg‐Hansen… - Liver …, 2023 - Wiley Online Library
Abstract Background & Aims Fatty liver disease has been associated with higher all‐cause
as well as liver‐related, ischemic heart disease (IHD)‐related and extrahepatic cancer …

NAFLD: An emerging causal factor for cardiovascular disease

M Li, H Wang, X Zhang, J Cai, H Li - Physiology, 2023 - journals.physiology.org
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease
worldwide that poses a significant threat to human health. Cardiovascular disease (CVD) is …