European Psychiatric Association guidance on assessment of cognitive impairment in schizophrenia

A Vita, W Gaebel, A Mucci, G Sachs, A Erfurth… - European …, 2022 - cambridge.org
Background Impairment in a wide range of cognitive abilities has been consistently reported
in individuals with schizophrenia. Both neurocognitive and social cognitive deficits are …

Quality of anticholinergic burden scales and their impact on clinical outcomes: a systematic review

A Lisibach, V Benelli, MG Ceppi… - European journal of …, 2021 - Springer
Purpose Older people are at risk of anticholinergic side effects due to changes affecting drug
elimination and higher sensitivity to drug's side effects. Anticholinergic burden scales (ABS) …

Anticholinergic medication burden–associated cognitive impairment in schizophrenia

YB Joshi, ML Thomas, DL Braff… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: Many psychotropic medications used to treat schizophrenia have significant
anticholinergic properties, which are linked to cognitive impairment and dementia risk in …

Gamma oscillations predict pro-cognitive and clinical response to auditory-based cognitive training in schizophrenia

JL Molina, ML Thomas, YB Joshi… - Translational …, 2020 - nature.com
Cognitive impairments are pervasive and disabling features of schizophrenia. Targeted
cognitive training (TCT) is a “bottom-up” cognitive remediation intervention with efficacy for …

Conceptualization and characterization of “primary” and “secondary” cognitive impairment in schizophrenia

A Vita, G Nibbio, S Barlati - Psychiatry Research, 2024 - Elsevier
Cognitive impairment represents one of the core features of schizophrenia, involves both
neurocognition and social cognition domains, and has a significant negative impact on real …

Sensitivity of schizophrenia endophenotype biomarkers to anticholinergic medication burden

YB Joshi, JL Molina, DL Braff… - American Journal of …, 2023 - Am Psychiatric Assoc
Methods Participants in the COGS-2 study have previously been described, including
inclusion and exclusion criteria (29). Participants were either healthy control subjects (HCS …

The prognostic utility of anticholinergic burden scales: an integrative review and gap analysis

HU Michael, O Enechukwu, MJ Brouillette, R Tamblyn… - Drugs & Aging, 2023 - Springer
Background Anticholinergic drugs are commonly prescribed, especially to older adults.
Anticholinergic burden scales (ABS) have been used to evaluate the cumulative effects of …

Medication impact on oral health in schizophrenia

L Urien, N Jauregizar, U Lertxundi… - … Oral, Patología Oral …, 2023 - pmc.ncbi.nlm.nih.gov
Background Patients with schizophrenia constitute a particularly vulnerable group for oral
diseases. Among the different factors involved, we aimed to examine the evidence of how …

Factors influencing the outcome of integrated therapy approach in schizophrenia: A narrative review of the literature

GM Giordano, F Brando, P Pezzella… - Frontiers in …, 2022 - frontiersin.org
The integration of pharmacotherapy with psychosocial interventions has an important role to
play in the improvement of functional outcome of subjects with schizophrenia (SCZ), in all …

[PDF][PDF] Less is more: deprescribing anticholinergic medications in persons with severe mental illness

AM Lupu, KL MacCamy, JM Gannon, JS Brar… - Ann Clin …, 2021 - aacp.com
BACKGROUND: Long-term prescribing of anticholinergic medications (ACM) for
antipsychotic-associated extrapyramidal symptoms (EPS) is not recommended, yet is widely …