Epithelial–mesenchymal transition (EMT) is a program wherein epithelial cells lose their
junctions and polarity while acquiring mesenchymal properties and invasive ability …

Epithelial to mesenchymal transition (EMT) occurs during the pathological process
associated with tumor progression and is considered to influence and promote the …

We performed a genome-wide association study of non-Hispanic, white individuals with
fibrotic idiopathic interstitial pneumonias (IIPs; n= 1,616) and controls (n= 4,683), with follow …

We present the largest whole-genome sequencing (WGS) study of non-small cell lung
cancer (NSCLC) to date among 6,004 individuals of Chinese ancestry, coupled with 23,049 …

Desmosomes are intercellular junctions, which preserve tissue integrity during homeostatic
and stress conditions. These functions rely on their unique structural properties, which …

Desmosomes are intercellular junctions that mediate cell–cell adhesion and anchor the
intermediate filament network to the plasma membrane, providing mechanical resilience to …

Widespread genome hypo-methylation and promoter hyper-methylation of epithelium-
specific genes are hallmarks of stable epithelial-to-mesenchymal transition (EMT), which in …

Abstract Background Keratins (KRTs) are intermediate filament proteins that interact with
multiple regulatory proteins to initiate signaling cascades. Keratin 13 (KRT13) plays an …

Integrating genomic data of multiple cancers allows de novo cancer grouping and
elucidating the shared genetic basis across cancers. Here, we conduct the pan-cancer and …

Desmosomes are cell-cell adhesive organelles with a well-known role in forming strong
intercellular adhesion during embryogenesis and in adult tissues subject to mechanical …