The degree of frailty as a translational measure of health in aging
Frailty is a multiply determined, age-related state of increased risk for adverse health
outcomes. We review how the degree of frailty conditions the development of late-life …
outcomes. We review how the degree of frailty conditions the development of late-life …
Frailty prevalence and impact on outcomes in patients with atrial fibrillation: a systematic review and meta-analysis of 1,187,000 patients
Frailty is a clinical syndrome characterized by a reduced physiologic reserve, increased
vulnerability to stressors and an increased risk of adverse outcomes. People with atrial …
vulnerability to stressors and an increased risk of adverse outcomes. People with atrial …
Atrial fibrillation and stroke prevention: 25 years of research at EP Europace journal
Stroke prevention in patients with atrial fibrillation (AF) is one pillar of the management of
this common arrhythmia. Substantial advances in the epidemiology and associated …
this common arrhythmia. Substantial advances in the epidemiology and associated …
Epidemiology and impact of frailty in patients with atrial fibrillation in Europe
Background Frailty is a medical syndrome characterised by reduced physiological reserve
and increased vulnerability to stressors. Data regarding the relationship between frailty and …
and increased vulnerability to stressors. Data regarding the relationship between frailty and …
Frailty and cardiovascular mortality in more than 3 million US Veterans
W Shrauner, EM Lord, XMT Nguyen… - European Heart …, 2022 - academic.oup.com
Aims Frailty is associated with an increased risk of all-cause mortality and cardiovascular
(CV) events. Limited data exist from the modern era of CV prevention on the relationship …
(CV) events. Limited data exist from the modern era of CV prevention on the relationship …
Atrial fibrillation: comorbidities, lifestyle, and patient factors
Modern anticoagulation therapy has dramatically reduced the risk of stroke and systemic
thromboembolism in people with atrial fibrillation (AF). However, AF still impairs quality of …
thromboembolism in people with atrial fibrillation (AF). However, AF still impairs quality of …
'Frailty as an adjective rather than a diagnosis'—identification of frailty in primary care: a qualitative interview study
A Seeley, M Glogowska, G Hayward - Age and Ageing, 2023 - academic.oup.com
Abstract Introduction In 2017, NHS England introduced proactive identification of frailty into
the General Practitioners (GP) contract. There is currently little information as to how this …
the General Practitioners (GP) contract. There is currently little information as to how this …
Implications of Clinical Risk Phenotypes on the Management and Natural History of Atrial Fibrillation: A Report From the GLORIA‐AF
Background Clinical risk factors are common among patients with atrial fibrillation (AF), but
there are still limited data on their association with oral anticoagulant (OAC) treatment …
there are still limited data on their association with oral anticoagulant (OAC) treatment …
[HTML][HTML] The introduction of direct oral anticoagulants has not resolved treatment gaps for frail patients with nonvalvular atrial fibrillation
M Orlandi, DC Dover, RK Sandhu, NM Hawkins… - Canadian Journal of …, 2022 - Elsevier
Background The extent to which the introduction of direct oral anticoagulants (DOACs)
influenced treatment patterns in frail and nonfrail patients with nonvalvular atrial fibrillation …
influenced treatment patterns in frail and nonfrail patients with nonvalvular atrial fibrillation …
Insights into the pharmacokinetics and pharmacodynamics of direct oral anticoagulants in older adults with atrial fibrillation: a structured narrative review
Older adults, the fastest growing population, represent almost 50% of all users of direct oral
anticoagulants (DOACs). Unfortunately, we have very little relevant pharmacological and …
anticoagulants (DOACs). Unfortunately, we have very little relevant pharmacological and …