One of the exciting movements in microbial sciences has been a refocusing and revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …
Neutrophil migration and its role during inflammation has been the focus of increased interest in the past decade. Advances in live imaging and the use of new model systems …
Natural products have been a rich source of compounds for drug discovery. However, their use has diminished in the past two decades, in part because of technical barriers to …
J Macheleidt, DJ Mattern, J Fischer… - Annual review of …, 2016 - annualreviews.org
Fungi have the capability to produce a tremendous number of so-called secondary metabolites, which possess a multitude of functions, eg, communication signals during …
I Kjærbølling, T Vesth, JC Frisvad, JL Nybo… - Nature …, 2020 - nature.com
Section Flavi encompasses both harmful and beneficial Aspergillus species, such as Aspergillus oryzae, used in food fermentation and enzyme production, and Aspergillus …
NP Keller - Nature chemical biology, 2015 - nature.com
Filamentous fungi are renowned for the production of a diverse array of secondary metabolites (SMs) where the genetic material required for synthesis of a SM is typically …
N Raffa, NP Keller - PLoS pathogens, 2019 - journals.plos.org
Aspergillus fumigatus is a ubiquitous saprophytic mold able to grow on a diversity of material ranging from decayed organic matter in the environment to space station cupolas [1]. Yet this …
Transgenic labeling of innate immune cell lineages within the larval zebrafish allows for real- time, in vivo analyses of microbial pathogenesis within a vertebrate host. To date, labeling of …
C Nai, V Meyer - Trends in microbiology, 2018 - cell.com
Since the onset of microbiology in the late 19th century, scientists have been growing microorganisms almost exclusively as pure cultures, resulting in a limited and biased view of …