Ultrafast magic angle spinning solid-state NMR spectroscopy: Advances in methodology and applications

Y Nishiyama, G Hou, V Agarwal, Y Su… - Chemical …, 2022 - ACS Publications
Solid-state NMR spectroscopy is one of the most commonly used techniques to study the
atomic-resolution structure and dynamics of various chemical, biological, material, and …

1H-Detected Biomolecular NMR under Fast Magic-Angle Spinning

T Le Marchand, T Schubeis, M Bonaccorsi… - Chemical …, 2022 - ACS Publications
Since the first pioneering studies on small deuterated peptides dating more than 20 years
ago, 1H detection has evolved into the most efficient approach for investigation of …

Structure of fully protonated proteins by proton-detected magic-angle spinning NMR

LB Andreas, K Jaudzems, J Stanek… - Proceedings of the …, 2016 - National Acad Sciences
Protein structure determination by proton-detected magic-angle spinning (MAS) NMR has
focused on highly deuterated samples, in which only a small number of protons are …

Fast magic-angle sample spinning solid-state NMR at 60–100 kHz for natural abundance samples

Y Nishiyama - Solid State Nuclear Magnetic Resonance, 2016 - Elsevier
In spite of tremendous progress made in pulse sequence designs and sophisticated
hardware developments, methods to improve sensitivity and resolution in solid-state NMR …

Proton-based ultrafast magic angle spinning solid-state NMR spectroscopy

R Zhang, KH Mroue… - Accounts of chemical …, 2017 - ACS Publications
Conspectus Protons are vastly abundant in a wide range of exciting macromolecules and
thus can be a powerful probe to investigate the structure and dynamics at atomic resolution …

Expanding the horizons for structural analysis of fully protonated protein assemblies by NMR spectroscopy at MAS frequencies above 100 kHz

J Struppe, CM Quinn, M Lu, M Wang, G Hou… - Solid state nuclear …, 2017 - Elsevier
The recent breakthroughs in NMR probe technologies resulted in the development of MAS
NMR probes with rotation frequencies exceeding 100 kHz. Herein, we explore dramatic …

Viscoelasticity and structures in chemically and physically dual-cross-linked hydrogels: insights from rheology and proton multiple-quantum NMR spectroscopy

X Zou, X Kui, R Zhang, Y Zhang, X Wang, Q Wu… - …, 2017 - ACS Publications
Hydrogels have received considerable attention as an innovative material due to their
widespread applications in various fields. As a soft and wet material, its mechanical …

Ultrafast 1H MAS NMR Crystallography for Natural Abundance Pharmaceutical Compounds

J Struppe, CM Quinn, S Sarkar… - Molecular …, 2019 - ACS Publications
Magic angle spinning (MAS) NMR is a powerful method for the study of pharmaceutical
compounds, and probes with spinning frequencies above 100 kHz enable an atomic …

[HTML][HTML] Role of the cell membrane interface in modulating production and uptake of Alzheimer's beta amyloid protein

P Bharadwaj, T Solomon, CJ Malajczuk… - … et Biophysica Acta (BBA …, 2018 - Elsevier
The beta amyloid protein (Aβ) plays a central role in Alzheimer's disease (AD) pathogenesis
and its interaction with cell membranes in known to promote mutually disruptive structural …

Conformations and intermolecular interactions in cellulose/silk fibroin blend films: a solid-state NMR perspective

D Tian, T Li, R Zhang, Q Wu, T Chen… - The Journal of …, 2017 - ACS Publications
Fabricating materials with excellent mechanical performance from the natural renewable
and degradable biopolymers has drawn significant attention in recent decades due to the …