Structure–function of type I and III interferons

NA de Weerd, AK Kurowska, JL Mendoza… - Current Opinion in …, 2024 - Elsevier
Type I and type III interferons (IFNs) are major components in activating the innate immune
response. Common to both are two distinct receptor chains (IFNAR1/IFNAR2 and …

Novel paradigm of therapeutic intervention for skin cancer: challenges and opportunities

M Nasim, M Khan, R Parveen, A Gull, S Khan… - Future Journal of …, 2024 - Springer
Background Skin cancer continues to be an imperative global health issue, urging
continuous exploration of treatment methodologies. Conventional treatments for skin cancer …

[HTML][HTML] Reconnoitring signaling pathways and exploiting innovative approaches tailoring multifaceted therapies for skin cancer

D Datta, S Sultana, J Strauss, A Puri, SP Bandi… - International Journal of …, 2024 - Elsevier
Nowadays, skin cancer is widespread just like a varied malignant cancer which can cause
serious health issues. Skin cancer, which encompasses malignant melanoma, basal cell …

Topical and Intralesional Immunotherapy for the Management of Basal Cell Carcinoma

A Fernández-Galván, P Rodríguez-Jiménez… - Cancers, 2024 - mdpi.com
Simple Summary Basal Cell Carcinoma is the most prevalent cancer in the white population,
with a 30% lifetime risk for individuals with fair skin. The main treatment goal is to completely …

Interferons: key modulators of the immune system in cancer

N Yusuf, SR Allie, BE Strauss - Frontiers in immunology, 2023 - frontiersin.org
This Research Topic brings to the forefront the expanding knowledge on mechanisms of anti-
tumor actions of interferons (IFNs) and their role in immunotherapy of cancers. IFNs …

Medicinal and Nutritional Importance of Curcuma longa in Human Health

S Shoaib, R Jahan, AS Rehman, M Shadab… - Medicinal Plants and …, 2024 - Springer
Curcuma longa or turmeric has been extensively studied for its diverse pharmacological
properties including anti-inflammatory, antioxidant, antimicrobial, and cardioprotective …

Mechanisms Regulating Type I Interferon Signaling in Human Keratinocytes Triggered by Exogenous DNA

R Uppala - 2023 - deepblue.lib.umich.edu
Activation of STING DNA sensing pathway triggers the production of type I interferons (IFNs)
in keratinocytes. In lupus keratinocytes, this pathway becomes overactive, leading to …