Medication adherence and blood pressure control: a scientific statement from the American Heart Association
The widespread treatment of hypertension and resultant improvement in blood pressure
have been major contributors to the dramatic age-specific decline in heart disease and …
have been major contributors to the dramatic age-specific decline in heart disease and …
Nonadherence in hypertension: how to develop and implement chemical adherence testing
Nonadherence to antihypertensive medication is common, especially in those with apparent
treatment-resistant hypertension (true treatment-resistant hypertension requires exclusion of …
treatment-resistant hypertension (true treatment-resistant hypertension requires exclusion of …
Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled …
Background Endovascular renal denervation reduces blood pressure in patients with mild-to-
moderate hypertension, but its efficacy in patients with true resistant hypertension has not …
moderate hypertension, but its efficacy in patients with true resistant hypertension has not …
Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham …
Background Catheter-based renal denervation has significantly reduced blood pressure in
previous studies. Following a positive pilot trial, the SPYRAL HTN-OFF MED (SPYRAL …
previous studies. Following a positive pilot trial, the SPYRAL HTN-OFF MED (SPYRAL …
Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial
Background Early studies suggest that radiofrequency-based renal denervation reduces
blood pressure in patients with moderate hypertension. We investigated whether an …
blood pressure in patients with moderate hypertension. We investigated whether an …
Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of …
DE Kandzari, M Böhm, F Mahfoud, RR Townsend… - The Lancet, 2018 - thelancet.com
Background Previous catheter-based renal denervation studies have reported variable
efficacy results. We aimed to evaluate safety and blood pressure response after renal …
efficacy results. We aimed to evaluate safety and blood pressure response after renal …
Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised …
RR Townsend, F Mahfoud, DE Kandzari, K Kario… - The Lancet, 2017 - thelancet.com
Background Previous randomised renal denervation studies did not show consistent efficacy
in reducing blood pressure. The objective of our study was to evaluate the effect of renal …
in reducing blood pressure. The objective of our study was to evaluate the effect of renal …
Effects of renal denervation on kidney function and long-term outcomes: 3-year follow-up from the Global SYMPLICITY Registry
F Mahfoud, M Böhm, R Schmieder… - European Heart …, 2019 - academic.oup.com
Aims Several studies and registries have demonstrated sustained reductions in blood
pressure (BP) after renal denervation (RDN). The long-term safety and efficacy after RDN in …
pressure (BP) after renal denervation (RDN). The long-term safety and efficacy after RDN in …
Catheter-based ultrasound renal denervation in patients with resistant hypertension: the randomized, controlled REQUIRE trial
K Kario, Y Yokoi, K Okamura, M Fujihara… - Hypertension …, 2022 - nature.com
Renal denervation is a promising new non-pharmacological treatment for resistant
hypertension. However, there is a lack of data from Asian patients. The REQUIRE trial …
hypertension. However, there is a lack of data from Asian patients. The REQUIRE trial …
Effect of alcohol-mediated renal denervation on blood pressure in the presence of antihypertensive medications: primary results from the TARGET BP I randomized …
DE Kandzari, MA Weber, A Pathak, JP Zidar… - Circulation, 2024 - ahajournals.org
BACKGROUND: Renal denervation (RDN) has demonstrated clinically relevant reductions
in blood pressure (BP) among individuals with uncontrolled hypertension despite lifestyle …
in blood pressure (BP) among individuals with uncontrolled hypertension despite lifestyle …