The metastasis is a multistep process in which a small proportion of cancer cells are
detached from the colony to enter into blood cells for obtaining a new place for metastasis …

Organs of future metastasis are not passive receivers of circulating tumor cells, but are
instead selectively and actively modified by the primary tumor before metastatic spread has …

Pancreatic cancer (PC) is one of the leading causes of cancer-related death worldwide due
to delayed diagnosis and limited treatments. More than 90% of all pancreatic cancers are …

Pancreatic cancer has the worst prognosis among common tumors which is attributed to its
aggressive phenotype, diagnosis at advanced, inoperable stages, and resistance to …

Pancreatic cancer (PC) is a devastating disease, offering poor mortality rates for patients.
The current challenge being faced is the inability to diagnose patients in a timely manner …

Exosomes, which are lipid membrane-enclosed nanovesicles (30− 150 nm in diameter),
contain abundant proteomic and genetic information. Specifically, tumor-derived exosomes …

Abstract Ethnopharmacological relevance Huaier (Trametes robiniophila Murr), a traditional
Chinese medicinal fungus, possesses potent anticancer efficacy and has been used as an …

Pancreatic ductal adenocarcinoma (PDAC) is a malignant tumor with invasive and
metastatic characteristics and poor prognosis. Intracellular protein homeostasis is …

Pancreatic cancer is a very aggressive and fatal malignancy with few therapeutic choices
and a poor prognosis. Understanding the molecular pathways that drive its growth is critical …

Gastrointestinal cancer (GIC) is the most prevalent and highly metastatic malignant tumor
and has a significant impact on mortality rates. Nevertheless, the swift advancement of …