The arthropod central complex and vertebrate basal ganglia derive from embryonic basal
forebrain lineages that are specified by an evolutionarily conserved genetic program leading …

▪ Abstract The forebrain comprises an intricate set of structures that are required for some of
the most complex and evolved functions of the mammalian brain. As a reflection of its …

The developing dorsomedial telencephalon includes the medial pallium, which goes on to
form the hippocampus. Generating a reliable source of human hippocampal tissue is an …

Human induced pluripotent stem cells (hiPSCs) are emerging as a tool for understanding
human brain development at cellular, molecular, and genomic levels. Here we show that …

The human nervous system is a highly complex but organized organ. The foundation of its
complexity and organization is laid down during regional patterning of the neural tube, the …

The conventional scheme of cortical formation shows that postmitotic neurons migrate away
from the germinal ventricular zone to their positions in the developing cortex, guided by the …

The prosomeric model attributes morphological meaning to gene expression patterns and
other data in the forebrain. It divides this territory into the same transverse segments …

Cerebral cortical functions are conducted by two general classes of neurons: glutamatergic
projection neurons and GABAergic interneurons. Distinct interneuron subtypes serve distinct …

Male embryonic mice with mutations in the X-linked aristaless-related homeobox gene (Arx)
developed with small brains due to suppressed proliferation and regional deficiencies in the …

Anteroposterior (AP) patterning of the vertebrate neural plate is initiated during gastrulation
and is regulated by Spemann's organizer and its derivatives. The prevailing model for AP …