Extrahepatic manifestations of HCV: the role of direct acting antivirals

ML Polo, N Laufer - Expert review of anti-infective therapy, 2017 - Taylor & Francis
ABSTRACT Introduction: Hepatitis C virus (HCV) represents a major health concern, as
nearly 3 million people become newly infected by this pathogen annually. The majority of …

Hepatitis C virus and its cutaneous manifestations: treatment in the direct‐acting antiviral era

LE Wiznia, ME Laird… - Journal of the European …, 2017 - Wiley Online Library
New all‐oral direct‐acting antivirals (DAA) have changed the hepatitis C virus (HCV)
treatment landscape. Given that dermatologists frequently encounter HCV‐infected patients …

Direct‐acting antivirals for hepatitis C virus induce a rapid clinical and biochemical remission of porphyria cutanea tarda

A Combalia, J To‐Figueras, M Laguno… - British Journal of …, 2017 - academic.oup.com
DEAR EDITOR, Sporadic porphyria cutanea tarda (PCT) is strongly associated with hepatitis
C virus (HCV) infection in our population. 1–4 Therapeutic options for PCT include …

Human oncoviruses: Mucocutaneous manifestations, pathogenesis, therapeutics, and prevention: Hepatitis viruses, human T-cell leukemia viruses, herpesviruses …

UN Mui, CT Haley, R Vangipuram, SK Tyring - Journal of the American …, 2019 - Elsevier
In 1964, the first human oncovirus, Epstein–Barr virus, was identified in Burkitt lymphoma
cells. Since then, 6 other human oncoviruses have been identified: human papillomavirus …

Ledipasvir/sofosbuvir is effective as sole treatment of porphyria cutanea tarda with chronic hepatitis C

HL Bonkovsky, SP Rudnick, CD Ma… - Digestive Diseases and …, 2023 - Springer
Abstract Background and Aims Chronic hepatitis C [CHC] is a risk factor for porphyria
cutanea tarda [PCT]. To assess whether ledipasvir/sofosbuvir is effective for treating both …

Association between hepatitis C virus and porphyria cutanea tarda

J To-Figueras - Molecular Genetics and Metabolism, 2019 - Elsevier
Porphyria cutanea tarda (PCT) arises from a deficiency of uroporphyrinogen decarboxylase
(UROD) in the liver. Several exogenous risk factors are associated with the acquired form of …

Porphyrias and photosensitivity: pathophysiology for the clinician

L Kakoullis, S Louppides… - Postgraduate …, 2018 - Taylor & Francis
Porphyrias are disorders caused by defects in the biosynthetic pathway of heme. Their
manifestations can be divided into three distinct syndromes, each attributable to the …

Evolution of HCV associated porphyria cutanea tarda after HCV sustained virologic response by direct acting antivirals

LJ García-Fraile, L García-Buey, CA Cerezo… - Gastroenterología y …, 2022 - Elsevier
Objectives Porphyria cutanea tarda (PCT) is common and usually associated with HCV
chronic infection and HFE polymorphisms. Since DAA IFN-free regimens availability, SVR …

Disappearance of multiple hyperechoic liver nodules in sporadic porphyria cutanea tarda after treatment with ledipasvir/sofosbuvir for hepatitis C

K Takata, S Shakado, K Sakamoto, H Fukuda… - Clinical Journal of …, 2017 - Springer
Ultrasonography in a 60-year-old man with chronic hepatitis C (CHC) demonstrated multiple
hyperechoic nodules. Radiological investigations did not reveal any signs of malignancy …

Hepatitis C viral infection and porphyria cutanea tarda

JP Callen - The American Journal of the Medical Sciences, 2017 - amjmedsci.com
Porphyria cutanea tarda (PCT) is the most common porphyria and has gained more
importance as the prevalence of hepatitis C viral infection rose. There are 2 categories of …