Heart failure with preserved ejection fraction: JACC scientific statement

BA Borlaug, K Sharma, SJ Shah, JE Ho - Journal of the American College …, 2023 - Elsevier
The incidence and prevalence of heart failure with preserved ejection fraction (HFpEF)
continue to rise in tandem with the increasing age and burdens of obesity, sedentariness …

Heart failure with preserved ejection fraction in perspective

MA Pfeffer, AM Shah, BA Borlaug - Circulation research, 2019 - Am Heart Assoc
Approximately half of the patients with signs and symptoms of heart failure have a left
ventricular ejection fraction that is not markedly abnormal. Despite the historically initial …

How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association …

B Pieske, C Tschöpe, RA De Boer… - European heart …, 2019 - academic.oup.com
Making a firm diagnosis of chronic heart failure with preserved ejection fraction (HFpEF)
remains a challenge. We recommend a new stepwise diagnostic process, the 'HFA–PEFF …

Heart failure with preserved ejection fraction

CE Hamo, C DeJong, N Hartshorne-Evans… - Nature reviews Disease …, 2024 - nature.com
Heart failure with preserved ejection fraction (HFpEF) accounts for nearly half of all heart
failure cases and has a prevalence that is expected to rise with the growing ageing …

Atrial dysfunction in patients with heart failure with preserved ejection fraction and atrial fibrillation

YNV Reddy, M Obokata, FH Verbrugge, G Lin… - Journal of the American …, 2020 - jacc.org
Background Paroxysmal and permanent atrial fibrillation (AF) are common in heart failure
with preserved ejection fraction (HFpEF). Objectives This study sought to determine the …

Research priorities for heart failure with preserved ejection fraction: national heart, lung, and blood institute working group summary

SJ Shah, BA Borlaug, DW Kitzman, AD McCulloch… - Circulation, 2020 - Am Heart Assoc
Heart failure with preserved ejection fraction (HFpEF), a major public health problem that is
rising in prevalence, is associated with high morbidity and mortality and is considered to be …

Exercise Intolerance in Patients With Heart Failure: JACC State-of-the-Art Review

MG Del Buono, R Arena, BA Borlaug, S Carbone… - Journal of the American …, 2019 - jacc.org
Exercise intolerance is the cardinal symptom of heart failure (HF) and is of crucial relevance,
because it is associated with a poor quality of life and increased mortality. While impaired …

Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction and obesity: a secondary analysis of the SUMMIT …

BA Borlaug, MR Zile, CM Kramer, SJ Baum, K Hurt… - Nature Medicine, 2024 - nature.com
Patients with obesity-related heart failure with preserved ejection fraction (HFpEF) display
circulatory volume expansion and pressure overload contributing to cardiovascular–kidney …

Heart failure with preserved ejection fraction: mechanisms and treatment strategies

K Omote, FH Verbrugge… - Annual review of medicine, 2022 - annualreviews.org
Approximately half of all patients with heart failure (HF) have a preserved ejection fraction,
and the prevalence is growing rapidly given the aging population in many countries and the …

Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review

A Pandey, SJ Shah, J Butler, DL Kellogg Jr… - Journal of the American …, 2021 - jacc.org
Exercise intolerance (EI) is the primary manifestation of chronic heart failure with preserved
ejection fraction (HFpEF), the most common form of heart failure among older individuals …