The potential of saliva as an accessible and sensitive sample type for the detection of respiratory pathogens and host immunity

CS Laxton, C Peno, AM Hahn, OM Allicock… - The Lancet …, 2023 - thelancet.com
Despite its prominence in early scientific records, the usefulness of saliva as a respiratory
specimen has been de-emphasised over the past century. However, due to its low cost and …

Colorimetric sensing for translational applications: from colorants to mechanisms

Z Jin, W Yim, M Retout, E Housel, W Zhong… - Chemical Society …, 2024 - pubs.rsc.org
Colorimetric sensing offers instant reporting via visible signals. Versus labor-intensive and
instrument-dependent detection methods, colorimetric sensors present advantages …

A DNA biosensors-based microfluidic platform for attomolar real-time detection of unamplified SARS-CoV-2 virus

P Robin, L Barnabei, S Marocco, J Pagnoncelli… - … and Bioelectronics: X, 2023 - Elsevier
The emergence of the coronavirus 2019 (COVID-19) arose the need for rapid, accurate and
massive virus detection methods to control the spread of infectious diseases. In this work, a …

[HTML][HTML] Saliva-based methods for SARS-CoV-2 testing in low-and middle-income countries

SH Tan, OM Allicock, A Katamba… - Bulletin of the World …, 2022 - ncbi.nlm.nih.gov
As the coronavirus disease 2019 (COVID-19) continues to disproportionately affect low-and
middle-income countries, the need for simple, accessible and frequent diagnostic testing …

[HTML][HTML] The emergence of saliva as a diagnostic and prognostic tool for viral infections

NF Oliveira Neto, RAV Caixeta, RM Zerbinati… - Viruses, 2024 - mdpi.com
Saliva has emerged as a promising diagnostic fluid for viral infections, enabling the direct
analysis of viral genetic material and the detection of infection markers such as proteins …

[HTML][HTML] Recent advances in RNA sample preparation techniques for the detection of SARS-CoV-2 in saliva and gargle

Y Liu, T Kumblathan, J Tao, J Xu, W Feng… - TrAC Trends in …, 2023 - Elsevier
Molecular detection of SARS-CoV-2 in gargle and saliva complements the standard analysis
of nasopharyngeal swabs (NPS) specimens. Although gargle and saliva specimens can be …

Advancements in SARS-CoV-2 testing: Enhancing accessibility through machine learning-enhanced biosensors

A Georgas, K Georgas, E Hristoforou - Micromachines, 2023 - mdpi.com
The COVID-19 pandemic highlighted the importance of widespread testing for SARS-CoV-2,
leading to the development of various new testing methods. However, traditional invasive …

Smartphone-based corona virus detection using saliva: a mini-review

H Ehtesabi, E Afzalpour - Heliyon, 2023 - cell.com
During the ongoing worldwide epidemic, SARS-CoV-2 has infected millions of individuals
and taken the lives of numerous victims. It is clear that early detection of infected individuals …

A multiplexed, paired-pooled droplet digital PCR assay for detection of SARS-CoV-2 in saliva

K Wagner, P Fox, E Gordon, W Hahn, K Olsen… - Scientific Reports, 2023 - nature.com
In response to the SARS-CoV-2 pandemic, we developed am ulti p lexed, p aired-p ool
droplet digital P CR (MP4) screening assay. Key features of our assay are the use of …

[HTML][HTML] Enhanced testing can substantially improve defence against several types of respiratory virus pandemic

J Petrie, JA Hay, O Srimokla, J Panovska-Griffiths… - Epidemics, 2025 - Elsevier
Mass testing to identify and isolate infected individuals is a promising approach for reducing
harm from the next acute respiratory virus pandemic. It offers the prospect of averting …