The shrinking brain: cerebral atrophy following traumatic brain injury

TC Harris, R De Rooij, E Kuhl - Annals of biomedical engineering, 2019 - Springer
Cerebral atrophy in response to traumatic brain injury is a well-documented phenomenon in
both primary investigations and review articles. Recent atrophy studies focus on exploring …

Inhibiting degradation of 2-arachidonoylglycerol as a therapeutic strategy for neurodegenerative diseases

C Chen - Pharmacology & therapeutics, 2023 - Elsevier
Endocannabinoids are endogenous lipid signaling mediators that participate in a variety of
physiological and pathological processes. 2-Arachidonoylglycerol (2-AG) is the most …

TDP-43 drives synaptic and cognitive deterioration following traumatic brain injury

F Gao, M Hu, J Zhang, J Hashem, C Chen - Acta neuropathologica, 2022 - Springer
Traumatic brain injury (TBI) has been recognized as an important risk factor for Alzheimer's
disease (AD). However, the molecular mechanisms by which TBI contributes to developing …

Cannabinoids in traumatic brain injury and related neuropathologies: preclinical and clinical research on endogenous, plant-derived, and synthetic compounds

BR Lins, CC Anyaegbu, SC Hellewell, M Papini… - Journal of …, 2023 - Springer
Traumatic brain injury is common, and often results in debilitating consequences. Even mild
traumatic brain injury leaves approximately 20% of patients with symptoms that persist for …

Concussion and long-term cognitive impairment among professional or elite sport-persons: a systematic review

V Gallo, K Motley, SPT Kemp, S Mian… - Journal of Neurology …, 2020 - jnnp.bmj.com
Introduction Understanding whether concussion in sport is associated with worsening
cognitive function in later life will likely have immediate repercussion on sports concussion …

Astrocytic degeneration in chronic traumatic encephalopathy

ET Hsu, M Gangolli, S Su, L Holleran, TD Stein… - Acta …, 2018 - Springer
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with
repeated head traumas. Using immunohistochemistry for glial fibrillary acidic protein as a …

Cannabidiol in sport: Ergogenic or else?

FX Gamelin, G Cuvelier, A Mendes, J Aucouturier… - Pharmacological …, 2020 - Elsevier
In the sports domain, cannabis is prohibited by the World Anti-Doping Agency (WADA)
across all sports in competition since 2004. The few studies on physical exercise and …

Structural neuroimaging in sport-related concussion

ED Bigler - International journal of psychophysiology, 2018 - Elsevier
Structural neuroimaging of athletes who have sustained a sports-related concussion (SRC)
can be viewed as either standard clinical imaging or with advanced neuroimaging methods …

Role of TREM2 in the development of neurodegenerative diseases after traumatic brain injury

C Zhang, S Chen - Molecular Neurobiology, 2023 - Springer
Traumatic brain injury (TBI) has been found as the primary cause of morbidity and disability
worldwide, which has posed a significant social and economic burden. The first stage of TBI …

Assessment of long-term effects of sports-related concussions: biological mechanisms and exosomal biomarkers

A Ledreux, MK Pryhoda, K Gorgens… - Frontiers in …, 2020 - frontiersin.org
Concussion or mild traumatic brain injury (mTBI) in athletes can cause persistent symptoms,
known as post-concussion syndrome (PCS), and repeated injuries may increase the long …