Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications
CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
Microbiome–microglia connections via the gut–brain axis
R Abdel-Haq, JCM Schlachetzki, CK Glass… - Journal of Experimental …, 2019 - rupress.org
Microglia, the resident immune cells in the brain, are essential for modulating neurogenesis,
influencing synaptic remodeling, and regulating neuroinflammation by surveying the brain …
influencing synaptic remodeling, and regulating neuroinflammation by surveying the brain …
[HTML][HTML] Plasma and fecal metabolite profiles in autism spectrum disorder
BD Needham, MD Adame, G Serena, DR Rose… - Biological …, 2021 - Elsevier
Background Autism spectrum disorder (ASD) is a neurodevelopmental condition with
hallmark behavioral manifestations including impaired social communication and restricted …
hallmark behavioral manifestations including impaired social communication and restricted …
Priming for life: early life nutrition and the microbiota-gut-brain axis
Microbes colonize the human body during the first moments of life and coexist with the host
throughout the lifespan. Intestinal microbiota and their metabolites aid in the programming of …
throughout the lifespan. Intestinal microbiota and their metabolites aid in the programming of …
Probiotics for gastrointestinal symptoms and quality of life in autism: a placebo-controlled pilot trial
LE Arnold, RA Luna, K Williams, J Chan… - Journal of child and …, 2019 - liebertpub.com
Objective: A randomized pilot trial of gastrointestinal (GI) symptoms targeting probiotic for
quality of life in autism spectrum disorder (ASD). Methods: Thirteen children, 3–12 years of …
quality of life in autism spectrum disorder (ASD). Methods: Thirteen children, 3–12 years of …
The brain-gut-microbiome system: pathways and implications for autism spectrum disorder
Gastrointestinal dysfunction is one of the most prevalent physiological symptoms of autism
spectrum disorder (ASD). A growing body of largely preclinical research suggests that …
spectrum disorder (ASD). A growing body of largely preclinical research suggests that …
Alteration of gut microbiota: new strategy for treating autism spectrum disorder
J Liu, Z Gao, C Liu, T Liu, J Gao, Y Cai… - Frontiers in cell and …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is defined as a complex heterogeneous disorder and
characterized by stereotyped behavior and deficits in communication and social interactions …
characterized by stereotyped behavior and deficits in communication and social interactions …
[HTML][HTML] Emerging mechanisms of valproic acid-induced neurotoxic events in autism and its implications for pharmacological treatment
A Taleb, W Lin, X Xu, G Zhang, QG Zhou… - Biomedicine & …, 2021 - Elsevier
Autism spectrum disorder (ASD) is a sort of mental disorder marked by deficits in cognitive
and communication abilities. To date no effective cure for this pernicious disease has been …
and communication abilities. To date no effective cure for this pernicious disease has been …
Germ-free animal experiments in the gut microbiota studies
T Uzbay - Current Opinion in Pharmacology, 2019 - Elsevier
Gut microbiota has a crucial role in the maintenance of health. Increasing evidence suggests
that changes or disturbances in gut microbiota may be associated with various diseases …
that changes or disturbances in gut microbiota may be associated with various diseases …
Conserving the holobiont
Organismal biology has undergone a dramatic paradigm shift in the last decade. The
realization that host cells and genes are outnumbered by symbiotic microbial cells and their …
realization that host cells and genes are outnumbered by symbiotic microbial cells and their …