Adjuvant and neoadjuvant therapy for breast cancer

T Shien, H Iwata - Japanese journal of clinical oncology, 2020 - academic.oup.com
Systemic therapies for operable breast cancer patients have improved outcomes and have
thus become standard treatments. Recently, new molecular target drugs and regimens are …

Prognostic value of different cut-off levels of Ki-67 in breast cancer: a systematic review and meta-analysis of 64,196 patients

F Petrelli, G Viale, M Cabiddu, S Barni - Breast cancer research and …, 2015 - Springer
A proliferative marker, expressed as the percentage of cells in a cell cycle, has been
developed and used as a discriminant of more aggressive malignant phenotypes in early …

Prognostic microRNA/mRNA signature from the integrated analysis of patients with invasive breast cancer

S Volinia, CM Croce - … of the National Academy of Sciences, 2013 - National Acad Sciences
The optimal management of breast cancer (BC) presents challenges due to the
heterogeneous molecular classification of the disease. We performed survival analysis on a …

TNM classification of malignant tumors (Breast Cancer Study Group)

M Sawaki, T Shien, H Iwata - Japanese journal of clinical …, 2019 - academic.oup.com
The eighth editions of the primary tumor, lymph node and metastasis classifications for
breast cancer issued by the American Joint Commission of Cancer and the Union for …

Modern classification of breast cancer: should we stick with morphology or convert to molecular profile characteristics

EA Rakha, IO Ellis - Advances in anatomic pathology, 2011 - journals.lww.com
Breast cancer represents a heterogeneous group of tumors with varied morphologic and
biological features, behavior, and response to therapy. The present routine clinical …

[HTML][HTML] Precision medicine in breast cancer

Y Naito, T Urasaki - Chinese Clinical Oncology, 2018 - cco.amegroups.org
Precision medicine is a strategy for disease treatment and prevention that considers
individual variability in genes, environment, and lifestyle. Historically, breast cancer has …

Nucleobindin 2 in human breast carcinoma as a potent prognostic factor

S Suzuki, K Takagi, Y Miki, Y Onodera… - Cancer …, 2012 - Wiley Online Library
It is well‐known that estrogens immensely contribute to the progression of human breast
carcinoma, but their detailed molecular mechanisms remain largely unclear. In this study, we …

Multi-gene classifiers for prediction of recurrence in breast cancer patients

Y Naoi, S Noguchi - Breast cancer, 2016 - Springer
Accurate prediction of recurrence risk is of vital importance for tailoring adjuvant
chemotherapy for individual breast cancer patients. Although recurrence risk has been …

Methylation of the SEPT9_v2 promoter as a novel marker for the detection of circulating tumor DNA in breast cancer patients

S Matsui, N Kagara, C Mishima, Y Naoi… - Oncology …, 2016 - spandidos-publications.com
The aim of the present study was to evaluate the promoter methylation status of SEPT9_v2
in breast cancer and to detect this methylated gene in circulating tumor DNA (ctDNA) in …

Validation of the prognosis of patients with ER‑positive, HER2‑negative and node‑negative invasive breast cancer classified as low risk by Curebest 95GC Breast …

Y Naoi, R Tsunashima, K Shimazu… - Oncology …, 2023 - spandidos-publications.com
Abstract Curebest™ 95GC breast (95GC) is a multigene classifier we developed for the
prognostic prediction of patients with estrogen receptor (ER)‑positive, human epidermal …