Vascular smooth muscle cells (VSMCs) are a major cell type present at all stages of an
atherosclerotic plaque. According to the 'response to injury'and 'vulnerable …

Flowing blood generates a frictional force called shear stress that has major effects on
vascular function. Branches and bends of arteries are exposed to complex blood flow …

The mechanisms that underlie superficial erosion, a cause of coronary thrombosis distinct
from plaque rupture, have garnered recent interest. In an era of improved control of …

Atherosclerosis, a chronic multifactorial disease, is closely related to the development of
cardiovascular diseases and is one of the predominant causes of death worldwide. Normal …

Objective—Coronary artery thrombosis can occur in the absence of plaque rupture because
of superficial erosion. Erosion-prone atheromata associate with more neutrophil …

To maintain physiological homeostasis, cell turnover occurs every day in the body via a form
of programmed cell death called apoptosis. During apoptosis, cells undergo distinct …

Blood vessels are exposed to multiple mechanical forces that are exerted on the vessel wall
(radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress) …

Aims Superficial erosion of atheromata causes many acute coronary syndromes, but arises
from unknown mechanisms. This study tested the hypothesis that Toll-like receptor-2 (TLR2) …

In contrast to their role in cell types with higher energy demands, mitochondria in endothelial
cells primarily function in signaling cellular responses to environmental cues. This article …

Fully bioresorbable scaffolds (BRS) were designed to overcome the limitations of metallic
drug-eluting stents, which permanently cage the vessel wall, thereby preventing normal …