Executive summary Acting now on dementia prevention, intervention, and care will vastly
improve living and dying for individuals with dementia and their families, and in doing so …

Behavioral and psychological symptoms of dementia include agitation, depression, apathy,
repetitive questioning, psychosis, aggression, sleep problems, wandering, and a variety of …

Currently, enhancement of cholinergic neurotransmission via cholinesterase inhibitors
represents the main available approach to treat cognitive and behavioural symptoms of the …

Importance Parkinson disease is the second most common neurodegenerative disease
worldwide. Although no available therapies alter the underlying neurodegenerative process …

Dementia is increasingly being recognized in cases of Parkinson's disease (PD); such cases
are termed PD dementia (PDD). The spread of fibrillar α-synuclein (α-syn) pathology from …

Dementia with Lewy bodies (DLB) and Parkinson's disease-dementia (PDD), although
sharing many clinical, neurochemical and morphological features, according to DSM-5, are …

In the long-term, with progression of the illness, Parkinson's disease dementia affects up to
90% of patients with Parkinson's disease. With increasing life expectancy in western …

Abstract α-Synuclein is an abundantly expressed neuronal protein that is at the center of
focus in understanding a group of neurodegenerative disorders called α-synucleinopathies …

Dementia is one of the most common and important aspects of Parkinson's disease and has
consequences for patients and caregivers, and has health-related costs. Mild cognitive …

The recent formalization of clinical criteria for Parkinson's disease with dementia (PDD)
codifies many studies on this topic, including those assessing biological correlates. These …