In this review, recent examples featuring C–H functionalization in the synthesis of complex
natural products are discussed. A focus is given to the way in which C–H functionalization …

This Perspective illustrates the defining characteristics of free radical chemistry, beginning
with its rich and storied history. Studies from our laboratory are discussed along with recent …

The past decade has witnessed the emergence of N-(acyloxy) phthalimides (NHPI esters)
and its derivatives at the forefront of synthetic methods facilitating the construction of diverse …

A practical electrochemical oxidation of unactivated C–H bonds is presented. This reaction
utilizes a simple redox mediator, quinuclidine, with inexpensive carbon and nickel …

Bolstered by recent advances in bioinformatics, genetics, and enzyme engineering, the field
of chemoenzymatic synthesis has enjoyed a rapid increase in popularity and utility. This …

Covering: 2012. Previous review: Nat. Prod. Rep., 2013, 30, 237–323. This review covers
the literature published in 2012 for marine natural products, with 1035 citations (673 for the …

Under oxidative conditions, 1, 4-dihydropyridines (DHPs) undergo a homolytic cleavage,
forming exclusively a Csp3-centered radical that can engage in the C–H alkylation of …

In the past decade, multiple catalytic C− H bond functionalization has been successfully
applied in natural product synthesis as a strategy to reduce the number of steps, increase …

Great efforts have been directed toward alkene π bond amination. In contrast, analogous
functionalization of the adjacent C (sp3)–C (sp2) σ bonds is much rarer. Here we report how …

Oxygen‐containing heterocycles are an important class of compounds with diverse
biological activities. In recent years, direct α‐C–H functionalization of inexpensive and …