Current understanding of epigenetics role in melanoma treatment and resistance

M Karami Fath, A Azargoonjahromi, A Soofi… - Cancer cell …, 2022 - Springer
Melanoma is the most aggressive form of skin cancer resulting from genetic mutations in
melanocytes. Several factors have been considered to be involved in melanoma …

[HTML][HTML] Chemotherapy-induced nephrotoxicity was improved by crocin in mouse model

Q Yin, H Xiong - European Journal of Histochemistry: EJH, 2022 - ncbi.nlm.nih.gov
Cisplatin (CDDP) has been widely used in cancer therapy, but it has been linked to side
effects such as nephrotoxicity. Crocin is a carotenoid found in crocus and gardenia flowers …

WIF1 was downregulated in cervical cancer due to promoter methylation

Y Wang, S Yuan, J Ma, H Liu, L Huang… - Acta Biochimica …, 2023 - abp.ptbioch.edu.pl
Abstract Wnt inhibitory factor 1 (WIF1) is frequently downregulated in a variety of cancer due
to promoter methylation. However, the methylation status of the WIF1 promoter in cervical …

Aberrant Heterochromatin Silences Immune Response Genes in Chronic Lymphocytic Leukemia

OM Depies, Q Guo, Y Gao, S Sinha, Z Ye… - Blood …, 2024 - ashpublications.org
Epigenetic alterations have been found in chronic lymphocytic leukemia (CLL), but the
functional importance of these changes remains underexplored. Here, we characterized the …

B cell receptor signaling drives APOBEC3 expression via direct enhancer regulation in chronic lymphocytic leukemia B cells

Z Wang, H Yan, JC Boysen, CR Secreto… - Blood cancer …, 2022 - nature.com
Constitutively activated B cell receptor (BCR) signaling is a primary biological feature of
chronic lymphocytic leukemia (CLL). The biological events controlled by BCR signaling in …

High expression of H2A histone family member Y promotes the proliferation and autophagy of hepatocellular carcinoma cells

J Lei, S Ma, W Sun, D Wang, Z Lu, D Zhang - Bioengineered, 2022 - Taylor & Francis
Hepatocellular carcinoma is a common malignant tumor and the third most common cause
of cancer-related deaths. In this study, we selected H2AFY as a potential oncogene from …

Oncolytic Adenovirus with SPAG9 shRNA Driven by DD3 Promoter Improved the Efficacy of Docetaxil for Prostate Cancer

M Lu, F Wei, C Wu, Z Xu, L Mao, D Yang - Journal of Oncology, 2022 - Wiley Online Library
Prostate cancer (PCa) is a common malignant tumor of the male urinary system and ranks
the second in the causes of tumor‐related deaths. Differential display code 3 (DD3) is a …

[PDF][PDF] Icotinib Enhanced Radiosensitization of Nasopharyngeal Carcinoma by Inhibiting the Expression of Epidermal Growth Factor Receptor

B Wu, H Xiong, Y Wang, S Zhao, H Lu… - … (Tech Science Press), 2022 - cdn.techscience.cn
Epidermal growth factor receptor (EGFR) is frequently overexpressed in multiple
malignancies. Icotinib (IH), a new EGFR tyrosine kinase inhibitor, enhances radiosensitivity …

[PDF][PDF] SCUOLA DI MEDICINA E CHIRURGIA

E CHIRURGICHE, PROF CAF - fedoa.unina.it
Uveal Melanoma (UM) is a rare intraocular neoplasia. It arises from atypical melanocytes of
the uveal tract, the concentric middle layer of the eye, consisting of the iris (in the anterior …