Aging is associated with an increased incidence of autoimmune diseases, despite the
progressive decline of immune responses (immunosenescence). This apparent paradox can …

Dynamically organized chromatin complexes often involve multiplex chromatin interactions
and sometimes chromatin-associated RNA,–. Chromatin complex compositions change …

Aging affects nearly all aspects of our cells, from our DNA to our proteins to how our cells
handle stress and communicate with each other. Age-related chromatin changes are of …

The highly and slightly condensed forms of chromatin, heterochromatin and euchromatin,
respectively, segregate in the cell nucleus. Heterochromatin is more abundant in the …

The mechanisms of aging are described at the molecular, cell, tissue, and systemic levels.
Primary age-dependent molecular lesions activate the cell stress response to compensate …

В обзоре рассмотрены механизмы старения на молекулярном, клеточном, тканевом и
системном уровнях. Первичные молекулярные повреждения вызывают клеточный …

While there is a prevalent genome organization in eukaryotic cells, with heterochromatin
concentrated at the nuclear periphery, anomalous cases do occur. Deviations of chromatin …

O envelhecimento é um evento natural para todo ser humano. Tem como característica ser
dinâmico, progressivo e universal e é caracterizado por alterações fisiológicas …

Although aging was long considered as a simple and unavoidable decay, accumulating
work over the last three decades have revealed that the process is not only highly regulated …