Numerous chronic diseases, such as cancer, diabetes, rheumatoid arthritis, cardiovascular
disease, and gastrointestinal disorders, all have an inflammation-based etiology. In cellular …

Galangin is an important flavonoid with natural activity, that is abundant in galangal and
propolis. Currently, various biological activities of galangin have been disclosed, including …

Purpose Myocardial ischemic reperfusion injury (MIRI) is a crucial clinical problem globally.
The molecular mechanisms of MIRI need to be fully explored to develop new therapeutic …

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are enzymes that
generate superoxide anion (O 2•-) and hydrogen peroxide (H 2 O 2), and that are widely …

Root canal treatment addresses infectious processes that require control. Occasionally, the
radicular pulp is vital and inflamed, presenting a superficial infection. To preserve pulpal …

Aims Limonin is a tetracyclic triterpenoid isolated from citrus fruits. Here, the effects of
limonin on cardiovascular abnormalities in nitric oxide-deficient rats induced by N ω-Nitrol …

Covering 2016 up to the end of 2023 Alpinia is the largest genus of flowering plants in the
ginger family, Zingiberaceae, and comprises about 500 species. Many Alpinia are …

Fenofibrate, a PPAR-α agonist clinically used to lower serum lipid levels, reduces cardiac
remodeling and improves cardiac function. However, its mechanism of action is not …

Here, the protective effect of antioxidant Idebenone (IDB) on renovascular hypertension was
studied. The two-kidney one-clip (2K-1C) model of renal hypertension was established. The …

Background and objective: Renovascular hypertension associated with vascular and kidney
dysfunctions have been reported. The possible mechanism might be related to oxidative …