The neuroprotective effects of exercise: maintaining a healthy brain throughout aging

LM Vecchio, Y Meng, K Xhima, N Lipsman… - Brain …, 2018 - content.iospress.com
Physical activity plays an essential role in maintaining a healthy body, yet it also provides
unique benefits for the vascular and cellular systems that sustain a healthy brain. While the …

Exercise training restores ischemic preconditioning in the aging heart

P Abete, C Calabrese, N Ferrara, A Cioppa… - Journal of the American …, 2000 - jacc.org
OBJECTIVES To investigate the effects of ischemic preconditioning in hearts from adult and
both sedentary and trained senescent rats. BACKGROUND Ischemic preconditioning does …

The neurobiological effects of senescence on dopaminergic system: a comprehensive review

GS Rocha, MAM Freire, KM Paiva, RF Oliveira… - Journal of Chemical …, 2024 - Elsevier
Over time, the body undergoes a natural, multifactorial, and ongoing process named
senescence, which induces changes at the molecular, cellular, and micro-anatomical levels …

[PDF][PDF] Биохимия продления жизни

АГ Голубев - Успехи геронтологии, 2003 - moscowuniversityclub.ru
Обзор биохимических механизмов, лежащих в основе известных способов продления
жизни и/или замедления скорости старения, приводит к выводу, что все они тем или …

Hypothalamic rAAV-mediated GDNF gene delivery ameliorates age-related obesity

N Tümer, PJ Scarpace, MD Dogan, CS Broxson… - Neurobiology of …, 2006 - Elsevier
Intraventricular delivery of glial cell line-derived neurotrophic factor (GDNF) results in weight
loss. We hypothesized that this effect of GDNF was likely mediated via its effects on …

Amelioratory effects of testosterone propionate supplement on behavioral, biochemical and morphological parameters in aged rats

R Cui, G Zhang, Y Kang, Q Cheng, H Tan, H Cui… - Experimental …, 2012 - Elsevier
Testosterone has been shown to affect motor behavior and nigrostriatal dopaminergic
(NSDA) system in young and adult male rats. However, it is not known whether exogenous …

Deficits in coordinated motor behavior and in nigrostriatal dopaminergic system ameliorated and VMAT2 expression up-regulated in aged male rats by administration …

L Wang, Y Kang, G Zhang, Y Zhang, R Cui… - Experimental …, 2016 - Elsevier
The effects of testosterone propionate (TP) supplements on the coordinated motor behavior
and nigrostriatal dopaminergic (NSDA) system were analyzed in aged male rats. The …

Antioxidant Gene Expression in Active and Sedentary House Mice (Mus domesticus) Selected for High Voluntary Wheel-Running Behavior

AM Bronikowski, TJ Morgan, T Garland Jr, PA Carter - Genetics, 2002 - academic.oup.com
We present liver mRNA levels of the two antioxidant enzymes catalase (CAT) and Mn-
superoxide dismutase (SOD2) in four treatment groups of house mice assayed by RNase …

Effects of life-long caloric restriction and voluntary exercise on age-related changes in levels of catecholamine biosynthetic enzymes and angiotensin II receptors in …

B Erdös, CS Broxson, T Landa, PJ Scarpace… - Experimental …, 2007 - Elsevier
We examined if life-long mild caloric restriction (CR) alone or with voluntary exercise
prevents the age-related changes in catecholamine biosynthetic enzyme levels in the …

Age-related biochemical dysfunction in 6-OHDA model rats subject to induced-endurance exercise

Z Rezaee, SM Marandi, F Esfarjani - Archives of Gerontology and Geriatrics, 2022 - Elsevier
Exercise can alleviate the disorders considered as the normal consequences of aging.
Whether or not the treadmill endurance training affects the biochemical markers in the …