Immunotherapy, specifically the introduction of immune checkpoint inhibitors, has
transformed the treatment of cancer, enabling long-term tumour control even in individuals …

Adult gliomas are aggressive brain tumours associated with low patient survival rates and
limited life expectancy. The most important hallmark of this type of tumour is its invasive …

Historically, the term “artificial intelligence” dates to 1956 when it was first used in a
conference at Dartmouth College in the US. Since then, the development of artificial …

The field of regenerative medicine is constantly advancing and aims to repair, regenerate, or
substitute impaired or unhealthy tissues and organs using cutting-edge approaches such as …

Radiotherapy is a primary therapeutic modality widely utilized with curative intent.
Traditionally tumor response was hypothesized to be due to high levels of cell death …

The synergy of radiation and the immune system is currently receiving significant attention in
oncology as numerous studies have shown that cancer irradiation can induce strong anti …

A large proportion of patients with cancer are unresponsive to treatment with immune
checkpoint blockade and other immunotherapies. Here, we report a mathematical model of …

Radiotherapy efficacy is the result of radiation-mediated cytotoxicity coupled with stimulation
of antitumor immune responses. We develop an in silico 3-dimensional agent-based model …

The role of genetic mutations in cancer is indisputable: They are a key source of tumor
heterogeneity and drive its evolution to malignancy. But, the success of these new mutant …

Artificial Intelligence (AI) reflects the intelligence exhibited by machines and software. It is a
highly desirable academic field of many current fields of studies. Leading AI researchers …