Exploring plant-based alpha-glucosidase inhibitors: promising contenders for combatting type-2 diabetes

S Kumari, R Saini, A Bhatnagar… - Archives of Physiology …, 2024 - Taylor & Francis
Objective This systematic review aimed to provide comprehensive details on the α-G
inhibitory potential of various bioactive compounds derived from natural sources. Methods A …

Natural α-glucosidase and protein tyrosine phosphatase 1B inhibitors: A source of scaffold molecules for synthesis of new multitarget antidiabetic drugs

M Genovese, I Nesi, A Caselli, P Paoli - Molecules, 2021 - mdpi.com
Diabetes mellitus (DM) represents a group of metabolic disorders that leads to acute and
long-term serious complications and is considered a worldwide sanitary emergence. Type 2 …

Comprehensive profiling of phenolic compounds and triterpenoid saponins from Acanthopanax senticosus and their antioxidant, α-glucosidase inhibitory activities

RH Kwon, H Na, JH Kim, SA Kim, SY Kim, HA Jung… - Scientific Reports, 2024 - nature.com
Acanthopanax senticosus belongs to Araliaceae family and is traditionally used as a tonic.
The roots and stems are mainly used as treatments for hypodynamia, rheumatism, and …

Exploring potential antidiabetic and anti-inflammatory flavonoids from Euphorbia humifusa with an integrated strategy

TF Rakotondrabe, M Fan, M Guo - Frontiers in Pharmacology, 2022 - frontiersin.org
E. humifusa Willd, a monoecious annual plant, native to Eastern Asia, has been traditionally
attributed to the treatment and prevention of miscellaneous diseases, including diabetes …

PTP1B-Inhibiting Branched-Chain Fatty Acid Dimers from Eremophila oppositifolia subsp. angustifolia Identified by High-Resolution PTP1B Inhibition Profiling and …

HA Pedersen, C Ndi, SJ Semple… - Journal of Natural …, 2020 - ACS Publications
Ten new branched-chain fatty acid (BCFA) dimers with a substituted cyclohexene structure,
five new monomers, and two known monomers,(2 E, 4 Z, 6 E)-5-(acetoxymethyl) tetradeca-2 …

2 (5H)-Furanone sesquiterpenes from Eremophila bignoniiflora: High-resolution inhibition profiling and PTP1B inhibitory activity

Y Zhao, L Kjaerulff, KT Kongstad, AM Heskes… - Phytochemistry, 2019 - Elsevier
Eremophila bignoniiflora is a shrub distributed throughout inland northern and eastern
Australia, and it has been used in several medicinal applications by some Australian …

[HTML][HTML] Potential of Myrtus communis Linn. as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS and …

C Liang, D Staerk, KT Kongstad - Journal of Functional Foods, 2020 - Elsevier
Myrtus communis Linn., an aromatic shrub widely distributed in Mediterranean littoral, is
traditionally used as a culinary herb and for manufacturing of the local Sardinian liquor …

Immobilized α-amylase magnetic beads for ligand fishing: Proof of concept and identification of α-amylase inhibitors in Ginkgo biloba

MJ Petersen, RCL Lima, L Kjaerulff, D Staerk - Phytochemistry, 2019 - Elsevier
Diabetes mellitus is a widespread metabolic disorder that affects millions of people around
the world. The disease is a major burden on both economic and social levels, and there is a …

Online coupling Fe3O4@ ZIF-67@ α-glucosidase biomicroreactor with high performance liquid chromatography for rapid screening of α-glucosidase inhibitors in tea …

X Wu, B Qiu, Y Chen, Y Shi, J Zhu, X Liu… - … of Chromatography B, 2020 - Elsevier
In this work, α-glucosidase was immobilized on a type of nanoscaled magnetic materials Fe
3 O 4@ ZIF-67 to construct a biomicroreactor for rapid screening α-glucosidase inhibitors …

Exploring the Potential of Myrcia Genus Essential Oils: A Review of Biological Activities and Recent Advances

EJB dos Santos, FWF Bezerra, LRR da Silva… - Molecules, 2024 - mdpi.com
The present study provides a comprehensive analysis of the chemical composition of
essential oils from species of the Myrcia genus and their applications. The compiled results …