The alarming rise in drug-resistant clinical cases of tuberculosis (TB) has necessitated the
rapid development of newer chemotherapeutic agents with novel mechanisms of action. The …

Chromanone or Chroman-4-one is the most important and interesting heterobicyclic
compound and acts as a building block in medicinal chemistry for isolation, designing and …

Photocatalytic carboxylation of alkenes with CO2 is a promising and sustainable strategy to
synthesize high value-added carboxylic acids. However, it is challenging and rarely …

Tuberculosis (TB) remains a serious threat to global public health, responsible for an
estimated 1.5 million mortalities in 2018. While there are available therapeutics for this …

The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) infections
is one of the most crucial challenges currently faced by the scientific community …

Among the various bacterial infections, tuberculosis (TB) remains a life-threatening
infectious disease responsible as the most significant cause of mortality and morbidity …

Tuberculosis (TB) is an infectious disease, infecting a quarter of world's population. Drug
resistant TB further exacerbates the grim scenario of the drying TB drug discovery pipeline …

Tuberculosis (TB) causes millions of deaths every year, ranking as one of the most
dangerous infectious diseases worldwide. Because several pathogenic strains of …

Tuberculosis (TB) is still a worldwide public health burden, as more than 1.3 million deaths
are expected to be reported in 2021. Even though almost 20 million patients have completed …

The Mg2+-dependent Mycobacterium tuberculosis salicylate synthase (MbtI) is a key
enzyme involved in the biosynthesis of siderophores. Because iron is essential for the …