A comprehensive review on tyrosinase inhibitors
S Zolghadri, A Bahrami, MT Hassan Khan… - Journal of enzyme …, 2019 - Taylor & Francis
Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and
plays an important role in the melanogenesis and enzymatic browning. Therefore, its …
plays an important role in the melanogenesis and enzymatic browning. Therefore, its …
Natural and synthetic flavonoid derivatives as new potential tyrosinase inhibitors: A systematic review
Tyrosinase is a multifunctional glycosylated and copper-containing oxidase that is highly
prevalent in plants and animals and plays a pivotal role in catalyzing the two key steps of …
prevalent in plants and animals and plays a pivotal role in catalyzing the two key steps of …
Targeting tyrosinase in hyperpigmentation: Current status, limitations and future promises
S Zolghadri, M Beygi, TF Mohammad… - Biochemical …, 2023 - Elsevier
Hyperpigmentation is a common and distressing dermatologic condition. Since tyrosinase
(TYR) plays an essential role in melanogenesis, its inhibition is considered a logical …
(TYR) plays an essential role in melanogenesis, its inhibition is considered a logical …
A systematic review of synthetic tyrosinase inhibitors and their structure-activity relationship
Z Peng, G Wang, QH Zeng, Y Li, H Liu… - Critical Reviews in …, 2022 - Taylor & Francis
Tyrosinase is a copper-containing oxidation enzyme, which is responsible for the production
of melanin. This enzyme is widely distributed in microorganisms, animals and plants, and …
of melanin. This enzyme is widely distributed in microorganisms, animals and plants, and …
Heterocyclic compounds as synthetic tyrosinase inhibitors: recent advances
Tyrosinase is a copper-containing enzyme which is widely distributed in nature (eg, bacteria,
mammals, fungi) and involved in two consecutive steps of melanin biosynthesis. In humans …
mammals, fungi) and involved in two consecutive steps of melanin biosynthesis. In humans …
Design and synthesis of novel pyrazole-phenyl semicarbazone derivatives as potential α-glucosidase inhibitor: Kinetics and molecular dynamics simulation study
A series of novel pyrazole-phenyl semicarbazone derivatives were designed, synthesized,
and screened for in vitro α-glucosidase inhibitory activity. Given the importance of hydrogen …
and screened for in vitro α-glucosidase inhibitory activity. Given the importance of hydrogen …
Synthesis and discovery of potential tyrosinase inhibitor of new coumarin‐based thiophenyl‐pyrazolylthiazole nuclei: In vitro evaluation, cytotoxicity, kinetic, and …
N Hosseini Nasab, H Raza, YS Eom… - Chemical Biology & …, 2023 - Wiley Online Library
A well‐known key enzyme in melanogenesis and hyperpigmentation is tyrosinase. The
present study introduces a novel series of thiophenyl‐pyrazolylthiazole‐coumarin hybrids …
present study introduces a novel series of thiophenyl‐pyrazolylthiazole‐coumarin hybrids …
Design, synthesis, in vitro, and in silico studies of novel benzylidene 6-methoxy-1-tetralone linked to benzyloxy and benzyl-1, 2, 3-triazole rings as potential tyrosinase …
Abstract Novel benzylidene 6-methoxy-1-tetralone derivatives linked to benzyloxy-and
benzyl-1, 2, 3-triazole rings were designed, synthesized, and evaluated as potential …
benzyl-1, 2, 3-triazole rings were designed, synthesized, and evaluated as potential …
[HTML][HTML] Facile synthesis of 4-aryl-N-(5-methyl-1H-pyrazol-3-yl) benzamides via Suzuki Miyaura reaction: antibacterial activity against clinically isolated NDM-1 …
The production of new pyrazole amide derivatives (6a-h) and their potential against New
Delhi metallo-β-lactamase-1 (NDM-1) producing bacteria was described in the present …
Delhi metallo-β-lactamase-1 (NDM-1) producing bacteria was described in the present …
In vitro cytotoxicity assay, mushroom tyrosinase inhibitory activity and release analysis of kojic monooleate nanodelivery system and in silico molecular docking study …
Tyrosinase is the main enzyme that catalyzes the browning of fruits, fungi and vegetables,
and melanogenesis process in mammals. Kojic monooleate (KMO) is an ester produced via …
and melanogenesis process in mammals. Kojic monooleate (KMO) is an ester produced via …