Epigenetic modification in diabetic kidney disease
Z Liu, J Liu, W Wang, X An, L Luo, D Yu… - Frontiers in …, 2023 - frontiersin.org
Diabetic kidney disease (DKD) is a common microangiopathy in diabetic patients and the
main cause of death in diabetic patients. The main manifestations of DKD are proteinuria …
main cause of death in diabetic patients. The main manifestations of DKD are proteinuria …
GABA alleviates high glucose-induced podocyte injury through dynamically altering the expression of macrophage M1/M2-derived exosomal miR-21a-5p/miR-25-3p
Y Zhuang, H Zheng, Y Yang, H Ni - Biochemical and Biophysical Research …, 2022 - Elsevier
Podocyte injury is the main clinical pathological feature of diabetic kidney disease (DKD).
The studies showed that DKD is associated with the polarization of macrophages to different …
The studies showed that DKD is associated with the polarization of macrophages to different …
[HTML][HTML] The progression from mild to severe hyperglycemia coupled with insulin resistance causes mitochondrial dysfunction and alters the metabolic secretome of …
Diabetic nephropathy (DN) and insulin resistance (IR) in kidney cells are considered main
causes for end-stage renal failure. However, it is unclear how IR affects early stages of the …
causes for end-stage renal failure. However, it is unclear how IR affects early stages of the …
Co-Analysis of Serum and Urine Differentially Expressed Proteins in Mucopolysaccharidosis Type I
K Liu, G Wan, Y Li, Z Liang, Y Meng… - Journal of Proteome …, 2024 - ACS Publications
Mucopolysaccharidosis type I (MPS I) is a lysosomal storage disease caused by the
deficiency of the enzyme α-l-iduronidase (IDUA), typically leading to devastating secondary …
deficiency of the enzyme α-l-iduronidase (IDUA), typically leading to devastating secondary …
Clinical and genetic determinants of diabetes and complications
S Li, M Delvecchio, KM Ramkumar, X Mao… - Frontiers in …, 2023 - frontiersin.org
Diabetes Mellitus (DM) continues to be a significant cause of death worldwide, imposing a
substantial burden on global public health. According to the data from International Diabetes …
substantial burden on global public health. According to the data from International Diabetes …
Uric acid mediates kidney tubular inflammation through the LDHA/ROS/NLRP3 pathway
J Ouyang, H Wang, Y Gan, J Huang - Clinical and Experimental …, 2024 - Taylor & Francis
Purpose Hyperuricemia (HUA) is an important factor leading to chronic kidney disease
(CKD). The kidney tubular inflammatory response is activated in HUA. This study aimed to …
(CKD). The kidney tubular inflammatory response is activated in HUA. This study aimed to …
Drug Repositioning Using Single-Cell RNA Sequencing in Cancer Research
Single-cell RNA sequencing (scRNA-seq) is a valuable tool for investigating cellular
dynamics at the transcriptome level, enabling researchers to delve into the interactions of …
dynamics at the transcriptome level, enabling researchers to delve into the interactions of …
Urine proteome uncover common mechanism between mucopolysaccharidosis type I and II
X Yuan, D Jia, Y Meng, J Duan - 2023 - researchsquare.com
Mucopolysaccharidosis (MPS) type I and II are two types of rare lysosomal storage diseases,
which lead to the accumulation of glycosaminoglycans due to the lack of the enzyme alpha …
which lead to the accumulation of glycosaminoglycans due to the lack of the enzyme alpha …