Cardiovascular diseases are one of the leading global causes of morbidity and mortality,
posing considerable health and economic burden on patients and medical systems …

Introduction Acute myocardial infarction (AMI) remains a leading cause of death in the
United States. The limited capacity of cardiomyocytes to regenerate and the restricted …

Extracellular vesicles (EVs) are nanosized particles with attractive therapeutic potential for
cardiac repair. However, low retention and stability after systemic administration limit their …

Human induced pluripotent stem cells (iPSCs) provide a virtually inexhaustible source of
starting material for next generation cell therapies, offering new opportunities for …

Introduction Knee osteoarthritis (KOA) is a highly prevalent disabling joint disease. Intra-
articular stem cell therapy is increasingly being used for treating KOA with little high-quality …

Abstract According to the World Health Organization (WHO), about 3.9 million people die
annually of ischemic heart disease (IHD). Several clinical trials have shown that stem cell …

Acute respiratory distress syndrome is an acute respiratory failure caused by cytokine
storms; highly pathogenic influenza A virus infection can induce cytokine storms. The innate …

The chronic liver diseases will slowly develop into liver fibrosis, cirrhosis, and even liver
cancer if no proper control is performed with high efficiency. Up to now, the most effective …

Idiopathic pulmonary fibrosis (IPF) is characterised by lung scarring and stiffening, for which
there is no effective cure. Based on the immunomodulatory and anti-fibrotic effects of …

Myocardial ischemia-reperfusion injury (MI/RI) constitutes a pivotal determinant impacting
the long-term prognosis of individuals afflicted by ischemic cardiomyopathy subsequent to …