Glioblastoma multiforme (GBM) is the most common and malignant of the glial tumors. The
world-wide estimates of new cases and deaths annually are remarkable, making GBM a …

The malignancy of glioblastoma (GBM), the most aggressive type of human brain tumor,
strongly correlates with the presence of hypoxic areas within the tumor mass. Oxygen levels …

Tissue hypoxia caused by upper airway collapse is a main cause of excessive oxidative
stress and systemic inflammation in obstructive sleep apnea (OSA) patients. Increased …

Glioblastoma (GBM), the most lethal form of brain tumors, bases its malignancy on the strong
ability of its cells to migrate and invade the narrow spaces of healthy brain parenchyma. Cell …

We demonstrate the application of a microfluidic platform combining spatiotemporal oxygen
control and long-term microscopy monitoring to observe tumour spheroid response to …

Regulatory volume decrease (RVD), a homeostatic process responsible for the re‐
establishment of the original cell volume upon swelling, is critical in controlling several …

Ion channels provide the basis for the nervous system's intrinsic electrical activity. Neuronal
excitability is a characteristic property of neurons and is critical for all functions of the …

Glioblastoma (GBM) cells express large‐conductance, calcium‐activated potassium (BK)
channels, whose activity is important for several critical aspects of the tumor, such as …

Malignant gliomas are the most common primary central nervous system tumors and their
prognosis is very poor. In recent years, ion channels have been demonstrated to play …

All cells are capable of secreting extracellular vesicles (EVs), which are not a means to
eliminate unneeded cellular compounds but represent a process to exchange material …