Detrusor underactivity and the underactive bladder: a systematic review of preclinical and clinical studies

NI Osman, F Esperto, CR Chapple - European urology, 2018 - Elsevier
Context Detrusor underactivity (DUA) is a common but relatively under-researched bladder
dysfunction. Underactive bladder (UAB) is the symptom-based correlate of DUA. Recently …

The link between vascular dysfunction, bladder ischemia, and aging bladder dysfunction

KE Andersson, DB Boedtkjer… - Therapeutic advances in …, 2017 - journals.sagepub.com
The vascular supply to the human bladder is derived mainly from the superior and inferior
vesical arteries, the latter being directly connected to the internal iliac artery. Aging is …

Magnetic soft robotic bladder for assisted urination

Y Yang, J Wang, L Wang, Q Wu, L Ling, Y Yang… - Science …, 2022 - science.org
The poor contractility of the detrusor muscle in underactive bladders (UABs) fails to increase
the pressure inside the UAB, leading to strenuous and incomplete urination. However …

Transient receptor potential channels in sensory mechanisms of the lower urinary tract

M Vanneste, A Segal, T Voets, W Everaerts - Nature Reviews Urology, 2021 - nature.com
Disruptions to sensory pathways in the lower urinary tract commonly occur and can give rise
to lower urinary tract symptoms (LUTS). The unmet clinical need for treatment of LUTS has …

When you say “Prostate”, don't forget to say “Bladder”!

L Cindolo, E Rubilotta, W Kuang… - Prostate Cancer and …, 2024 - nature.com
Earlier this year, Dr Wayne Kuang published on his website (Published by ManVsProstate;
www. ManVsProstate. com; Contact at: DrWayneKuang@ ManVsProstate. com; First Edition …

Underactive bladder, detrusor underactivity, definition, symptoms, epidemiology, etiopathogenesis, and risk factors

R Aldamanhori, CR Chapple - Current opinion in urology, 2017 - journals.lww.com
DUA and its associated symptoms and signs are still poorly recognized entities. Difficulty
and confusion arise in properly diagnosing DUA, as at present it can only be accurately …

Underactive bladder and detrusor underactivity: New advances and prospectives

J Wang, L Ren, X Liu, J Liu, Q Ling - International Journal of Molecular …, 2023 - mdpi.com
Underactive bladder (UAB) is a prevalent but under-researched lower urinary tract symptom
that typically occurs alongside detrusor underactivity (DU). Unlike UAB, DU is a urodynamic …

[HTML][HTML] Intravesical activation of the cation channel TRPV4 improves bladder function in a rat model for detrusor underactivity

Y Deruyver, E Weyne, K Dewulf, R Rietjens, S Pinto… - European Urology, 2018 - Elsevier
Background Improvement of bladder emptying by modulating afferent nerve activity is an
attractive therapeutic strategy for detrusor underactivity. Transient receptor potential vanilloid …

Investigating urine biomarkers in detrusor underactivity and detrusor overactivity with detrusor underactivity patients

YH Jiang, JF Jhang, YH Wu, HC Kuo - Biomedicines, 2023 - mdpi.com
Bladder inflammation and tissue hypoxia were considered important pathognomonic
bladder features in detrusor underactivity (DU) and detrusor overactivity (DO) patients. This …

[HTML][HTML] Understanding underactive bladder: a review of the contemporary literature

M Santos-Pereira, A Charrua - Porto Biomedical Journal, 2020 - journals.lww.com
Underactive bladder (UAB) is characterized by prolonged voiding, hesitancy, and slow
and/or intermittent stream with or without a sensation of incomplete bladder emptying. The …