Pre-eclampsia

E Dimitriadis, DL Rolnik, W Zhou… - Nature reviews Disease …, 2023 - nature.com
Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …

Preeclampsia pathophysiology and adverse outcomes during pregnancy and postpartum

C Bisson, S Dautel, E Patel, S Suresh, P Dauer… - Frontiers in …, 2023 - frontiersin.org
Background Preeclampsia is a disease with far-reaching consequences that extend beyond
the immediate postpartum period and have a significant impact later in life. Preeclampsia …

Radicals, oxidative/nitrosative stress and preeclampsia

S Taysi, AS Tascan, MG Ugur… - Mini reviews in medicinal …, 2019 - ingentaconnect.com
Preeclampsia (PE) has a profound effect in increasing both maternal and fetal morbidity and
mortality especially in third World. Disturbances of extravillous trophoblast migration toward …

Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome)

BM Sibai, MK Ramadan, I Usta, M Salama… - American journal of …, 1993 - Elsevier
Objective: Our purpose was to describe the incidence and effects of serious obstetric
complications on maternal outcome in pregnancies complicated by HELLP syndrome. Study …

Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count

BM Sibai - Obstetrics & Gynecology, 2004 - journals.lww.com
Hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome has been
recognized as a complication of preeclampsia—eclampsia for decades. Recognition of this …

Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this …

Y Zhou, CH Damsky, SJ Fisher - The Journal of clinical …, 1997 - Am Soc Clin Investig
In human pregnancy, placental cytotrophoblasts that invade the uterus downregulate the
expression of adhesion receptors that are characteristic of their epithelial origin, and …

Cellular immune responses in the pathophysiology of preeclampsia

D Miller, K Motomura, J Galaz… - Journal of Leukocyte …, 2022 - academic.oup.com
Preeclampsia, defined as new-onset hypertension accompanied by proteinuria occurring at
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …

The HELLP syndrome: clinical issues and management. A Review

K Haram, E Svendsen, U Abildgaard - BMC pregnancy and childbirth, 2009 - Springer
Background The HELLP syndrome is a serious complication in pregnancy characterized by
haemolysis, elevated liver enzymes and low platelet count occurring in 0.5 to 0.9% of all …

HELLP syndrome—holistic insight into pathophysiology

A Petca, BC Miron, I Pacu, MC Dumitrașcu… - Medicina, 2022 - mdpi.com
HELLP syndrome, also known as the syndrome of hemolysis, elevated liver enzymes, and
low platelets, represents a severe pregnancy complication typically associated with …

Hypertensive disorders in twin versus singleton gestations

BM Sibai, J Hauth, S Caritis, MD Lindheimer… - American journal of …, 2000 - Elsevier
Objective: This study was undertaken to compare rates and severity of gestational
hypertension and preeclampsia, as well as perinatal outcomes when these complications …