Small cell lung cancer (SCLC) is an aggressive form of lung cancer characterized by dismal
prognosis. Although SCLC may initially respond well to platinum-based chemotherapy, it …

Histones are DNA‐binding basic proteins found in chromosomes. After the histone
translation, its amino tail undergoes various modifications, such as methylation, acetylation …

Breast cancer is the most prevalent cancer worldwide, and metastasis is the leading cause
of death in cancer patients. Human monocyte chemoattractant protein-1 (MCP-1/CCL2) was …

Dysregulated epigenetic modifications dynamically drive the abnormal transcription process
to affect the tumor microenvironment; thus, promoting cancer progression, drug resistance …

Immune checkpoint blockade (ICB) is regarded as a promising strategy for cancer therapy.
The histone methyltransferase, Enhancer of Zeste Homolog 2 (EZH2), has been implicated …

In recent years, the tumour microenvironment (TME) of solid tumours has attracted more and
more attention from researchers, especially those non-tumour components such as immune …

Small-cell lung cancer (SCLC) is a very aggressive neuroendocrine tumor with a poor
prognosis. Whereas immunotherapy has emerged as a promising approach for treating …

Small cell lung cancer (SCLC) is a recalcitrant, relatively immune-cold, and deadly subtype
of lung cancer. SCLC has been viewed as a single or homogenous disease that includes …

A large amount of research has proven that monocyte chemotactic protein‑1 (MCP‑1) is
associated with different types of disease, including autoimmune, metabolic and …

The tumor microenvironment (TME) is a complex interconnected network of immune cells,
fibroblasts, blood vessels, and extracellular matrix surrounding the tumor. Because of its …