CASK, which belongs to the family of membrane-associated guanylate kinase (MAGUK)
proteins, is recognized as a multidomain scaffolding protein highly expressed in the …

Eukaryotic cell membrane dynamics change in curvature during physiological and
pathological processes. In the past ten years, a novel protein family, Fes/CIP4 homology …

Objective Crohn9s disease (CD) is an intractable inflammatory bowel disease (IBD) of
unknown cause. Recent meta-analysis of the genome-wide association studies (GWAS) and …

First described in 1974, FG syndrome (FGS) is an X-linked multiple congenital
anomaly/mental retardation (MCA/MR) disorder, characterized by high clinical variability and …

MAGUK with inverted domain structure-1 (MAGI-1) is a membrane-associated protein with
one guanylate kinase, six PSD-95/Dlg-A/ZO-1 (PDZ), and two WW domains and is localized …

Mammalian FCHSD1 and FCHSD2 are homologous proteins containing an amino-terminal
F-BAR domain and two SH3 domains near their carboxyl-termini. We report here that …

Calcium/calmodulin-dependent serine protein kinase (CASK) is a conserved multi-domain
scaffolding protein involved in brain development, synapse formation, and establishment of …

Background CADM1 encodes an immunoglobulin superfamily (IGSF) cell adhesion
molecule. Inactivation of CADM1, either by promoter hypermethylation or loss of …

The E6 oncoproteins from high‐risk mucosal human papillomavirus (HPV) induce cervical
cancer via two major activities, the binding and the degradation of the p53 protein and PDZ …

Simple Summary MAGI1, 2, and 3 belong to a subgroup of the MAGUK family of scaffolding
proteins, and are comprised of 6 PDZ domains, 2 WW domains, and 1 GUK domain. MAGIs …