Advances in MALDI mass spectrometry imaging single cell and tissues

X Zhu, T Xu, C Peng, S Wu - Frontiers in Chemistry, 2022 - frontiersin.org
Compared with conventional optical microscopy techniques, mass spectrometry imaging
(MSI) or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique …

Primary aldosteronism: state-of-the-art review

A Vaidya, GL Hundemer, K Nanba… - American Journal of …, 2022 - academic.oup.com
We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …

[PDF][PDF] Activation of the pentose phosphate pathway in macrophages is crucial for granuloma formation in sarcoidosis

S Nakamizo, Y Sugiura, Y Ishida, Y Ueki… - Journal of Clinical …, 2023 - Am Soc Clin Investig
Sarcoidosis is a disease of unknown etiology in which granulomas form throughout the body
and is typically treated with glucocorticoids, but there are no approved steroid-sparing …

Advanced tandem mass spectrometry in metabolomics and lipidomics—methods and applications

S Heiles - Analytical and Bioanalytical Chemistry, 2021 - Springer
Metabolomics and lipidomics are new drivers of the omics era as molecular signatures and
selected analytes allow phenotypic characterization and serve as biomarkers, respectively …

Recent developments of novel matrices and on-tissue chemical derivatization reagents for MALDI-MSI

Q Zhou, A Fülöp, C Hopf - Analytical and bioanalytical chemistry, 2021 - Springer
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is a fast-
growing technique for visualization of the spatial distribution of the small molecular and …

Multimodal imaging mass spectrometry: next generation molecular mapping in biology and medicine

EK Neumann, KV Djambazova… - Journal of the …, 2020 - ACS Publications
Imaging mass spectrometry has become a mature molecular mapping technology that is
used for molecular discovery in many medical and biological systems. While powerful by …

On‐tissue chemical derivatization in mass spectrometry imaging

C Harkin, KW Smith, FL Cruickshank… - Mass spectrometry …, 2022 - Wiley Online Library
Mass spectrometry imaging (MSI) combines molecular and spatial information in a valuable
tool for a wide range of applications. Matrix‐assisted laser desorption/ionization (MALDI) is …

What are we imaging? Software tools and experimental strategies for annotation and identification of small molecules in mass spectrometry imaging

G Baquer, L Sementé, T Mahamdi… - Mass Spectrometry …, 2023 - Wiley Online Library
Mass spectrometry imaging (MSI) has become a widespread analytical technique to perform
nonlabeled spatial molecular identification. The Achilles' heel of MSI is the annotation and …

Mass spectrometry imaging for spatially resolved multi-omics molecular mapping

H Zhang, KH Lu, M Ebbini, P Huang, H Lu, L Li - npj Imaging, 2024 - nature.com
The recent upswing in the integration of spatial multi-omics for conducting multidimensional
information measurements is opening a new chapter in biological research. Mapping the …

Carbon dots-nanosensors: Advancement in food traceability for a sustainable environmental development

Z Shafi, VK Pandey, R Singh, S Rustagi - Food Control, 2024 - Elsevier
The increasing complexity of global food networks and the possible hazards of fraud,
foodborne diseases, and environmental damage highlight the need for strong food …