Ratiometric optical nanoprobes enable accurate molecular detection and imaging

X Huang, J Song, BC Yung, X Huang… - Chemical Society …, 2018 - pubs.rsc.org
Exploring and understanding biological and pathological changes are of great significance
for early diagnosis and therapy of diseases. Optical sensing and imaging approaches have …

Stimuli-responsive drug delivery systems triggered by intracellular or subcellular microenvironments

T Sun, C Jiang - Advanced Drug Delivery Reviews, 2023 - Elsevier
Drug delivery systems (DDS) triggered by local microenvironment represents the state-of-art
of nanomedicine design, where the triggering hallmarks at intracellular and subcellular …

Cu single atom nanozyme based high‐efficiency mild photothermal therapy through cellular metabolic regulation

M Chang, Z Hou, M Wang, D Wen, C Li… - Angewandte …, 2022 - Wiley Online Library
Upregulation of heat shock proteins (HSPs) drastically compromises the treatment effect of
mild photothermal therapy (PTT). Herein, we designed a polyporous Cu single atom …

ATP‐responsive smart hydrogel releasing immune adjuvant synchronized with repeated chemotherapy or radiotherapy to boost antitumor immunity

L Sun, F Shen, L Tian, H Tao, Z Xiong, J Xu… - Advanced …, 2021 - Wiley Online Library
Certain chemotherapeutics and forms of ionizing radiation can induce immunogenic cell
death (ICD). If there simultaneously exist immune adjuvants within the tumor, such antitumor …

Recent progress in the development of upconversion nanomaterials in bioimaging and disease treatment

G Liang, H Wang, H Shi, H Wang, M Zhu, A Jing… - Journal of …, 2020 - Springer
Multifunctional lanthanide-based upconversion nanoparticles (UCNPs), which feature
efficiently convert low-energy photons into high-energy photons, have attracted …

Harnessing endogenous stimuli for responsive materials in theranostics

AB Cook, P Decuzzi - ACS nano, 2021 - ACS Publications
Materials that respond to endogenous stimuli are being leveraged to enhance
spatiotemporal control in a range of biomedical applications from drug delivery to diagnostic …

Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications

JG Croissant, Y Fatieiev, A Almalik… - Advanced healthcare …, 2018 - Wiley Online Library
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …

Precise nanomedicine for intelligent therapy of cancer

H Chen, Z Gu, H An, C Chen, J Chen, R Cui… - Science China …, 2018 - Springer
Precise nanomedicine has been extensively explored for efficient cancer imaging and
targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and …

Lanthanide-activated nanoparticles: a toolbox for bioimaging, therapeutics, and neuromodulation

Z Yi, Z Luo, X Qin, Q Chen, X Liu - Accounts of Chemical Research, 2020 - ACS Publications
Conspectus Owing to their unique features, the past decade has witnessed rapid
developments of lanthanide-activated nanoparticles for biological applications. These …

Prodrug-inspired adenosine triphosphate–activatable celastrol-Fe (III) chelate for cancer therapy

H Li, Y Li, L Zhang, N Wang, D Lu, D Tang, Y Lv… - Science …, 2024 - science.org
Celastrol (CEL), an active compound isolated from the root of Tripterygium wilfordii, exhibits
broad anticancer activities. However, its poor stability, narrow therapeutic window and …