The involvement of RNA interference (RNAi) in heterochromatin formation has become clear largely through studies in the fission yeast Schizosaccharomyces pombe and plants like …
Parasites and infectious diseases are everywhere and represent some of the most potent forces shaping the natural world. They affect almost every aspect imaginable in the life of …
A pioneering proposal for a pluralistic extension of evolutionary theory, now updated to reflect the most recent research This updated edition of the widely read Evolution in Four …
Both microRNAs (miRNA) and small interfering RNAs (siRNA) share a common set of cellular proteins (Dicer and the RNA-induced silencing complex [RISC]) to elicit RNA …
G Meister, M Landthaler, A Patkaniowska, Y Dorsett… - Molecular cell, 2004 - cell.com
Argonaute proteins associate with small RNAs that guide mRNA degradation, translational repression, or a combination of both. The human Argonaute family has eight members, four …
In animals, the double-stranded RNA-specific endonuclease Dicer produces two classes of functionally distinct, tiny RNAs: microRNAs (miRNAs) and small interfering RNAs (siRNAs) …
R Sunkar, JK Zhu - The Plant Cell, 2004 - academic.oup.com
MicroRNAs (miRNAs) and short interfering RNAs (siRNAs) are small noncoding RNAs that have recently emerged as important regulators of mRNA degradation, translational …
Plants with altered microRNA metabolism have pleiotropic developmental defects, but direct evidence for microRNAs regulating specific aspects of plant morphogenesis has been …
J Martinez, A Patkaniowska, H Urlaub, R Lührmann… - Cell, 2002 - cell.com
Small interfering RNAs (siRNAs) are the mediators of mRNA degradation in the process of RNA interference (RNAi). Here, we describe a human biochemical system that recapitulates …