Recent scientific evidence suggests that food proteins not only serve as nutrients, but can
also modulate the body's physiological functions. These physiological functions are primarily …

In this contribution, we review the molecular and physiological barriers to oral delivery of
peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …

Melittin, the main venom component of the European Honeybee, is a cationic linear peptide-
amide of 26 amino acid residues with the sequence: GIGAVLKVLTTGLPALISWIKRKRQQ …

Intestinal permeation enhancers (PEs) are one of the most widely tested strategies to
improve oral delivery of therapeutic peptides. This article assesses the intestinal permeation …

Salcaprozate sodium (SNAC) and sodium caprate (C10) are two of the most advanced
intestinal permeation enhancers (PEs) that have been tested in clinical trials for oral delivery …

The development of oral dosage forms that allows absorption of therapeutic peptides to the
systemic circulation is one of the greatest challenges for the pharmaceutical industry …

The use of chemical permeation enhancers (PEs) is the most widely tested approach to
improve oral absorption of low permeability active agents, as represented by peptides …

A major challenge in oral drug delivery is the development of novel dosage forms to promote
absorption of poorly permeable drugs across the intestinal epithelium. To date, no …

Surfactants are a diverse group of compounds that share the capacity to adsorb at the
boundary between distinct phases of matter. They are used as pharmaceutical excipients …

Abstract Labrasol® ALF (Labrasol®), is a non-ionic surfactant excipient primarily used as a
solubilising agent. It was investigated here as an intestinal permeation enhancer in isolated …