Progress and promise of nitric oxide‐releasing platforms

T Yang, AN Zelikin, R Chandrawati - Advanced Science, 2018 - Wiley Online Library
Nitric oxide (NO) is a highly potent radical with a wide spectrum of physiological activities.
Depending on the concentration, it can enhance endothelial cell proliferation in a growth …

Detection and quantification of nitric oxide–derived oxidants in biological systems

MN Möller, N Rios, M Trujillo, R Radi… - Journal of biological …, 2019 - ASBMB
The free radical nitric oxide (NO•) exerts biological effects through the direct and reversible
interaction with specific targets (eg soluble guanylate cyclase) or through the generation of …

Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo

H Bischof, M Rehberg, S Stryeck, K Artinger… - Nature …, 2017 - nature.com
Abstract Changes in intra-and extracellular potassium ion (K+) concentrations control many
important cellular processes and related biological functions. However, our current …

[HTML][HTML] Redox-related biomarkers in human cardiovascular disease-classical footprints and beyond

A Daiber, O Hahad, I Andreadou, S Steven, S Daub… - Redox Biology, 2021 - Elsevier
Global epidemiological studies show that chronic non-communicable diseases such as
atherosclerosis and metabolic disorders represent the leading cause of premature mortality …

Upconversion nanoprobes for the ratiometric luminescent sensing of nitric oxide

N Wang, X Yu, K Zhang, CA Mirkin… - Journal of the American …, 2017 - ACS Publications
By taking advantage of the optical properties of upconversion nanoparticles (UCNPs), we
have designed a luminescence ratiometric nanosensor for measuring nitric oxide (NO) in …

Nitric oxide acts as a cotransmitter in a subset of dopaminergic neurons to diversify memory dynamics

Y Aso, RP Ray, X Long, D Bushey, K Cichewicz… - Elife, 2019 - elifesciences.org
Animals employ diverse learning rules and synaptic plasticity dynamics to record temporal
and statistical information about the world. However, the molecular mechanisms underlying …

[HTML][HTML] Nrf2-regulated redox signaling in brain endothelial cells adapted to physiological oxygen levels: consequences for sulforaphane mediated protection against …

G Warpsinski, MJ Smith, S Srivastava, TP Keeley… - Redox Biology, 2020 - Elsevier
Ischemic stroke is associated with a surge in reactive oxygen species generation during
reperfusion. The narrow therapeutic window for the delivery of intravenous thrombolysis and …

Astrocytes produce nitric oxide via nitrite reduction in mitochondria to regulate cerebral blood flow during brain hypoxia

IN Christie, SM Theparambil, A Braga, M Doronin… - Cell reports, 2023 - cell.com
During hypoxia, increases in cerebral blood flow maintain brain oxygen delivery. Here, we
describe a mechanism of brain oxygen sensing that mediates the dilation of …

Live-cell imaging of physiologically relevant metal ions using genetically encoded FRET-based probes

H Bischof, S Burgstaller, M Waldeck-Weiermair… - Cells, 2019 - mdpi.com
Essential biochemical reactions and processes within living organisms are coupled to
subcellular fluctuations of metal ions. Disturbances in cellular metal ion homeostasis are …

Recommendations on terminology and experimental best practice associated with plant nitric oxide research

KJ Gupta, JT Hancock, M Petrivalsky, Z Kolbert… - New …, 2020 - Wiley Online Library
Nitric oxide (NO) emerged as a key signal molecule in plants. During the last two decades
impressive progress has been made in plant NO research. This small, redox‐active …