Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission
The concept of the antibiotic resistome was introduced just over a decade ago, and since
then, active resistome studies have been conducted. In the present study, we describe the …
then, active resistome studies have been conducted. In the present study, we describe the …
The threat of antimicrobial resistance on the human microbiome
L Brinkac, A Voorhies, A Gomez, KE Nelson - Microbial ecology, 2017 - Springer
Ubiquitous in nature, antimicrobial resistance (AMR) has existed long before the golden age
of antimicrobials. While antimicrobial agents are beneficial to combat infection, their …
of antimicrobials. While antimicrobial agents are beneficial to combat infection, their …
Maternal gut and breast milk microbiota affect infant gut antibiotic resistome and mobile genetic elements
The infant gut microbiota has a high abundance of antibiotic resistance genes (ARGs)
compared to adults, even in the absence of antibiotic exposure. Here we study potential …
compared to adults, even in the absence of antibiotic exposure. Here we study potential …
Potential effects of horizontal gene exchange in the human gut
A Lerner, T Matthias, R Aminov - Frontiers in immunology, 2017 - frontiersin.org
Many essential functions of the human body are dependent on the symbiotic microbiota,
which is present at especially high numbers and diversity in the gut. This intricate host …
which is present at especially high numbers and diversity in the gut. This intricate host …
Class 1 integrons as invasive species
MR Gillings - Current Opinion in Microbiology, 2017 - Elsevier
Highlights•Clinical class 1 integrons are descended from a single, recent ancestor.•They
have rapidly spread between diverse bacteria, vertebrate hosts and countries.•This spread …
have rapidly spread between diverse bacteria, vertebrate hosts and countries.•This spread …
Microbiome as a tool and a target in the effort to address antimicrobial resistance
DA Relman, M Lipsitch - Proceedings of the National …, 2018 - National Acad Sciences
Reciprocal, intimate relationships between the human microbiome and the host immune
system are shaped by past microbial encounters and prepare the host for future ones …
system are shaped by past microbial encounters and prepare the host for future ones …
Early microbiota, antibiotics and health
AM Nogacka, N Salazar, S Arboleya, M Suárez… - Cellular and molecular …, 2018 - Springer
The colonization of the neonatal digestive tract provides a microbial stimulus required for an
adequate maturation towards the physiological homeostasis of the host. This colonization …
adequate maturation towards the physiological homeostasis of the host. This colonization …
Incompatibility group I1 (IncI1) plasmids: their genetics, biology, and public health relevance
Bacterial plasmids are extrachromosomal genetic elements that often carry antimicrobial
resistance (AMR) genes and genes encoding increased virulence and can be transmissible …
resistance (AMR) genes and genes encoding increased virulence and can be transmissible …
Persistence of birth mode-dependent effects on gut microbiome composition, immune system stimulation and antimicrobial resistance during the first year of life
Caesarean section delivery (CSD) disrupts mother-to-neonate transmission of specific
microbial strains and functional repertoires as well as linked immune system priming. Here …
microbial strains and functional repertoires as well as linked immune system priming. Here …
Microbial transmission from mother to child: improving infant intestinal microbiota development by identifying the obstacles
Industrialisation has introduced several lifestyle changes and medical advancements but
their impact on intestinal microbiota acquisition is often overlooked. Even though these …
their impact on intestinal microbiota acquisition is often overlooked. Even though these …