Drug-eluting implants are one of the leading implant technologies to facilitate the healing
capacity of bones by eliminating implant-associated infections. Treatment of the infections …

Fracture-related infection (FRI) remains a challenging complication that imposes a heavy
burden on orthopaedic trauma patients. The surgical management eradicates the local …

Aims Chronic osteomyelitis may recur if dead space management, after excision of infected
bone, is inadequate. This study describes the results of a strategy for the management of …

We report our experience using a biodegradable calcium sulphate antibiotic carrier
containing tobramycin in the surgical management of patients with chronic osteomyelitis …

The use of local antibiotics for the prevention of infection in the setting of open fractures and
as part of the treatment of osteomyelitis is well established. Antibiotics are most commonly …

Objectives: We sought to compare the effectiveness of an antibiotic-impregnated
bioabsorbable bone substitute (BBS, tobramycin-impregnated medical-grade calcium …

Calcium sulphate has been used extensively as a bioabsorbable bone substitute for 90
years. Its advantages include its low cost, ready availability and unlimited supply, lack of …

Local release of antibiotic has advantages in the treatment of chronic osteomyelitis and
infected fractures. The adequacy of surgical debridement is still key to successful clearance …

Some of the earliest success in de novo tissue generation was in bone tissue, and
advances, facilitated by the use of endogenous and exogenous progenitor cells, continue …

Implantable devices have improved the lives of many patients, but implant-associated
infection remains a serious complication with significant morbidity and mortality. In recent …