Stem cell-based therapies have emerged as a promising approach for treating various
neurological disorders by harnessing the regenerative potential of stem cells to restore …

Stem cell transplantation offers a promising therapy that can be administered days, weeks,
or months after a stroke. We recognize 2 major mitigating factors that remain unresolved in …

Background Human mesenchymal stromal cell (MSC)-derived extracellular vesicles (EV)
revealed neuroprotective potentials in various brain injury models, including neonatal …

Stroke is a leading cause of death in the US and around the world but with limited treatment
options. Survivors often present with long-term cognitive and neurological deficits. Stem cell …

The use of biologics in various diseases has dramatically increased in recent years. Stroke,
a cerebrovascular disease, is the second most common cause of death, and the leading …

Systemic transplantation of mesenchymal stem cells (MSCs) is a promising approach for the
treatment of ischemia-associated disorders, including stroke. However, exact mechanisms …

We studied therapeutic efficacy and migration characteristics of mesenchymal stem cells
isolated from the human placenta after their intracerebral (stereotactic) administration to rats …

With global warming, extreme environmental heat is becoming a social issue of concern,
which can cause adverse health results including heatstroke (HS). Severe heat stress is …

Chronic cerebral ischemia (CCI) results in a prolonged insufficient blood supply to the brain
tissue, leading to impaired neuronal function and subsequent impairment of cognitive and …

Pluripotent neural stem or progenitor cells (NSC/NPC) have been reported in the brains of
adult preclinical models for decades, as have mesenchymal stem/stromal cells (MSC) been …