Over the past decades, a large number of drugs as well as drug candidates with poor
dissolution characteristics have been witnessed, which invokes great interest in enabling …

Most of the newly developed drug candidates are lipophilic and poorly water-soluble.
Enhancing the dissolution and bioavailability of these drugs is a major challenge for the …

Famotidine (FMD) is a highly potent H 2-receptor antagonist used in peptic ulcer treatment.
However, the drug possesses poor aqueous solubility and permeability. FMD-loaded solid …

Sažetak Many modern drugs are poorly water soluble substances, which causes difficulties
in the development of solid dosage forms with sufficient bioavailability. Preparation of …

The present investigation was performed to develop a rifampicin (RIF)-loaded solidified self-
nanoemulsifying drug delivery system (SNEDDS)(solidified RIF-OF1) for in vitro and in vivo …

Bigels of sunflower oil, span 40 and water soluble synthetic polymers (eg polyvinyl alcohol
and polyvinyl pyrrolidone) were prepared and explored as controlled delivery vehicle for …

The purpose of this study is to develop solid self-nanoemulsifying drug delivery systems (S-
SNEDDS) for oral bioavailability enhancement of Clopidogrel (CLP). CLP is an anti-platelet …

Efavirenz displays low and variable bioavailability because of its poor aqueous solubility
and high log P-value. The present investigation was aimed to improve the dissolution profile …

High specific surface area (SSA), porous structure, and suitable technological characteristics
(flow, compressibility) predetermine powder carriers to be used in pharmaceutical …

Hydrochlorothiazide (HCTZ) is a class IV BCS drug that exhibits varying bioavailability due
to poor solubility and low permeability. The first part of the present investigation was aimed …