[HTML][HTML] Neutrophils in tuberculosis-associated inflammation and lung pathology

CN Muefong, JS Sutherland - Frontiers in immunology, 2020 - frontiersin.org
Protective immunity to Mycobacterium tuberculosis (Mtb)—the causative agent of
tuberculosis (TB)—is not fully understood but involves immune responses within the …

Glutathione: Role in oxidative/nitrosative stress, antioxidant defense, and treatments

S Raj Rai, C Bhattacharyya, A Sarkar… - …, 2021 - Wiley Online Library
Glutathione (GSH) is the most abundant cellular tripeptide (L‐γ‐glutamate‐L‐cysteinyl‐
glycine) which is as critical as oxygen and water. This low molecular mass antioxidant has a …

Glutathione and infection

D Morris, M Khurasany, T Nguyen, J Kim… - … et Biophysica Acta (BBA …, 2013 - Elsevier
BACKGROUND: The tripeptide γ-glutamylcysteinylglycine or glutathione (GSH) has
demonstrated protective abilities against the detrimental effects of oxidative stress within the …

[HTML][HTML] Mechanisms of Control of Mycobacterium tuberculosis by NK Cells: Role of Glutathione

M Allen, C Bailey, I Cahatol, L Dodge, J Yim… - Frontiers in …, 2015 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tb), continues to be one of the
most prevalent infectious diseases in the world. There is an upward trend in occurrence due …

[HTML][HTML] Immunomodulatory effects of glutathione, garlic derivatives, and hydrogen sulfide

C Rodrigues, SS Percival - Nutrients, 2019 - mdpi.com
Glutathione and aged garlic extract are sulfur-containing products that play important
protective and regulatory roles within the immune system and in oxidative processes …

[HTML][HTML] Investigating the causes for decreased levels of glutathione in individuals with type II diabetes

M Lagman, J Ly, T Saing, M Kaur Singh… - PloS one, 2015 - journals.plos.org
Tuberculosis (TB) remains an eminent global burden with one third of the world's population
latently infected with Mycobacterium tuberculosis (M. tb). Individuals with compromised …

[HTML][HTML] Targeting molecular inflammatory pathways in granuloma as host-directed therapies for tuberculosis

R Guler, M Ozturk, S Sabeel, B Motaung… - Frontiers in …, 2021 - frontiersin.org
Globally, more than 10 million people developed active tuberculosis (TB), with 1.4 million
deaths in 2020. In addition, the emergence of drug-resistant strains in many regions of the …

[HTML][HTML] The immune response in tubercular uveitis and its implications for treatment: From anti-tubercular treatment to host-directed therapies

I Putera, B Schrijver, JCEM Ten Berge, V Gupta… - Progress in Retinal and …, 2023 - Elsevier
Tubercular uveitis (TB-uveitis) remains a conundrum in the uveitis field, which is mainly
related to the diverse clinical phenotypes of TB-uveitis. Moreover, it remains difficult to …

[HTML][HTML] Glutathione modulates efficacious changes in the immune response against tuberculosis

A Abnousian, J Vasquez, K Sasaninia, M Kelley… - Biomedicines, 2023 - mdpi.com
Glutathione (GSH) is an antioxidant in human cells that is utilized to prevent damage
occurred by reactive oxygen species, free radicals, peroxides, lipid peroxides, and heavy …

[HTML][HTML] Neutrophil-dependent immunity during pulmonary infections and inflammations

CY Effah, EK Drokow, C Agboyibor, L Ding… - Frontiers in …, 2021 - frontiersin.org
Rapid recruitment of neutrophils to an inflamed site is one of the hallmarks of an effective
host defense mechanism. The main pathway through which this happens is by the innate …