Virus infection induces different cellular responses in infected cells. These include cellular
stress responses like autophagy and unfolded protein response (UPR). Both autophagy and …

HIV-1 employs a rich arsenal of viral factors throughout its life cycle and co-opts intracellular
trafficking pathways. This exquisitely coordinated process requires precise manipulation of …

Development of the messenger RNA (mRNA) vaccine has emerged as an effective and
speedy strategy to control the spread of new pathogens. After vaccination, the mRNA is …

Neurological diseases are multifactorial, devastating diseases that are causative for various
neurodegenerative disorders. Emerging evidence points that accumulation of unfolded …

Unfolded protein response (UPR) is an evolutionarily conserved pathway triggered during
perturbation of endoplasmic reticulum (ER) homeostasis in response to the accumulation of …

Symptomatic dengue virus (DENV) infections range from mild fever to severe haemorrhagic
disease and death. Host‐viral interactions play a significant role in deciding the fate of the …

Several human diseases including viral infections activate the unfolded protein response
(UPR) due to abnormal accumulation of unfolded/misfolded proteins. However, UPR …

HIV-associated cerebrovascular events remain highly prevalent even in the current era of
antiretroviral therapy (ART). We hypothesize that low-level HIV replication and associated …

In eukaryotic cells, the endoplasmic reticulum is particularly important in post-translational
modification of proteins before they are released extracellularly or sent to another …

Mounting evidence suggests that antiretroviral drugs may contribute to the persistence of
HIV-associated neurocognitive disorders (HAND), which impact 30%–50% of HIV-infected …