Cutaneous wound healing is the process by which skin repairs itself. It is generally accepted
that cutaneous wound healing can be divided into 4 phases: haemostasis, inflammation …

Shikonin is the major bioactive component extracted from the roots of Lithospermum
erythrorhizon which is also known as “Zicao” in Traditional Chinese Medicine (TCM). Recent …

Shikonin and its derivatives, isolated from traditional medicinal plant species of the genus
Lithospermum, Alkanna, Arnebia, Anchusa, Onosma, and Echium belonging to the …

Background Shikonin is one of the major phytochemical components of Lithospermum
erythrorhizon (Purple Cromwell), which is a type of medicinal herb broadly utilized in …

The non-communicable disease, cancer, is one of the major causes of death across the
world and is forecast to increase by 75% to reach close to 25 million cases over the next two …

Phytochemicals gained considerable interest during the past years as source to develop
new treatment options for chemoprevention and cancer therapy. Motivated by the fact that a …

The naphthoquinone shikonin is the main active principle of Zicao, a traditional Chinese
herbal medicine made from the dried root of Lithospermum erythrorhizon. Studies carried …

One of the leading global causes of death is cancer; even though several treatment methods
have improved survival rates, the incidence and fatality rates remain high. Naphthoquinones …

Chronic kidney diseases generally lead to renal fibrosis. Despite great progress having
been made in identifying molecular mediators of fibrosis, the mechanism that governs renal …

Skin is the largest organ of the human body. Being the interface between the body and the
outer environment, makes it susceptible to physical injury. To maintain life, nature has …