The core promoter: At the heart of gene expression

YM Danino, D Even, D Ideses… - Biochimica et Biophysica …, 2015 - Elsevier
The identities of different cells and tissues in multicellular organisms are determined by
tightly controlled transcriptional programs that enable accurate gene expression. The …

Control of translation initiation in animals

NK Gray, M Wickens - Annual review of cell and developmental …, 1998 - annualreviews.org
▪ Abstract Regulation of translation initiation is a central control point in animal cells. We
review our current understanding of the mechanisms of regulation, drawing particularly on …

CPEB is a specificity factor that mediates cytoplasmic polyadenylation during Xenopus oocyte maturation

LE Hake, JD Richter - Cell, 1994 - cell.com
The translational activation of several maternal mRNAs during Xenopus oocyte maturation is
stimulated bycytoplasmic poly (A) elongation, which requires the uri: dine-rich cytoplasmic …

Relaxed selection and the rapid evolution of reproductive genes

AL Dapper, MJ Wade - Trends in Genetics, 2020 - cell.com
Evolutionary genomic studies find that reproductive protein genes, those directly involved in
reproductive processes, diversify more rapidly than most other gene categories. Strong …

Emergent dynamics of adult stem cell lineages from single nucleus and single cell RNA-Seq of Drosophila testes

AA Raz, GS Vida, SR Stern, S Mahadevaraju… - Elife, 2023 - elifesciences.org
Proper differentiation of sperm from germline stem cells, essential for production of the next
generation, requires dramatic changes in gene expression that drive remodeling of almost …

Coordinate Initiation of Drosophila Development by Regulated Polyadenylation of Maternal Messenger RNAs

FJ Salles, ME Lieberfarb, C Wreden, JP Gergen… - Science, 1994 - science.org
Pattern formation in Drosophila depends initially on the translational activation of maternal
messenger RNAs (mRNAs) whose protein products determine cell fate. Three mRNAs that …

[HTML][HTML] A possible meiotic function of the peculiar patterns of gene expression in mammalian spermatogenic cells

KC Kleene - Mechanisms of development, 2001 - Elsevier
This review focuses on the striking differences in the patterns of transcription and translation
in somatic and spermatogenic cells in mammals. In early haploid cells, mRNA translation …

High divergence of reproductive tract proteins and their association with postzygotic reproductive isolation in Drosophila melanogaster and Drosophila virilis group …

A Civetta, RS Singh - Journal of Molecular Evolution, 1995 - Springer
The possible association between gonadal protein divergence and postzygotic reproductive
isolation was investigated among species of the Drosophila melanogaster and D. virilis …

Proteins binding to 5′ untranslated region sites: a general mechanism for translational regulation of mRNAs in human and yeast cells

R Stripecke, CC Oliveira, JEG Mccarthy… - Molecular and cellular …, 1994 - Taylor & Francis
We demonstrate that a bacteriophage protein and a spliceosomal protein can be converted
into eukaryotic translational repressor proteins. mRNAs with binding sites for the …

The Drosophila don juan (dj) gene encodes a novel sperm specific protein component characterized by an unusual domain of a repetitive amino acid motif

A Santel, T Winhauer, N Blümer… - Mechanisms of …, 1997 - Elsevier
We identified and characterized the don juan gene (dj) of Drosophila melanogaster. The don
juan gene codes for a sperm specific protein component with an unusual repetitive six …